Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 6/20 | 0.37 |
| ▸ | IGF1R | P08069 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.32 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | PPARA | Q07869 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7765458 | 1.00 | KCNH2 (0.37) | KCNH2IGF1RALOX15L3MBTL1MAOB | |
| SCHEMBL7765453 | 1.00 | KCNH2 (0.37) | KCNH2IGF1RALOX15L3MBTL1MAOB | |
| SCHEMBL7769973 | 0.93 | KCNH2 (0.41) | KCNH2IGF1RALOX15ITGB3ITGA2B | |
| SCHEMBL7769964 | 0.93 | KCNH2 (0.41) | KCNH2IGF1RALOX15ITGB3ITGA2B | |
| SCHEMBL7769969 | 0.93 | KCNH2 (0.41) | KCNH2IGF1RALOX15ITGB3ITGA2B | |
| SCHEMBL7769784 | 0.90 | HRH3 (0.33) | MAOBITGB3ITGA2BHRH3LMNA | |
| SCHEMBL7769787 | 0.90 | HRH3 (0.33) | MAOBITGB3ITGA2BHRH3LMNA | |
| SCHEMBL7769781 | 0.90 | HRH3 (0.33) | MAOBITGB3ITGA2BHRH3LMNA | |
| SCHEMBL8018501 | 0.88 | MAOB (0.40) | L3MBTL1MAOBFAAH | |
| SCHEMBL7762546 | 0.88 | MAOB (0.34) | MAOBPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0727428-B1 | Novel silacyclohexane compounds, preparation thereof, liquid crystal compositions comprising the same, and liquid crystal devices comprising the compositions | SHINETSU CHEMICAL CO (JP) | 2001-06-06 | — | — | EP | disclosed |
| US-5665271-A | Silacyclohexane compounds, preparation thereof, liquid crystal compositions comprising the same, and liquid crystal devices comprising the compositions | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1997-09-09 | — | — | US | disclosed |
| EP-0727428-A1 | Novel silacyclohexane compounds, preparation thereof, liquid crystal compositions comprising the same, and liquid crystal devices comprising the compositions | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1996-08-21 | — | — | EP | disclosed |