SCHEMBL8018501

SCHEMBL8018501

CCC[Si@H]1CC[C@H]([C@H]2CC[C@H](CCc3ccc(-c4ccc(Cl)cc4)cc3)CC2)CC1

nearest known ligand 0.40

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MAOB P27338 3/20 0.40
FAAH O00519 1/20 0.35
MAOA P21397 1/20 0.34
GPR84 Q9NQS5 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.32
SLC6A3 Q01959 1/20 0.32
DRD2 P14416 2/20 0.31
DRD3 P35462 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8018499 1.00 MAOB (0.40) MAOBFAAHMAOAGPR84L3MBTL1
SCHEMBL8018504 1.00 MAOB (0.40) MAOBFAAHMAOAGPR84L3MBTL1
SCHEMBL8096069 0.92 MAOB (0.43) MAOBFAAHMAOAGPR84L3MBTL1
SCHEMBL8096072 0.92 MAOB (0.43) MAOBFAAHMAOAGPR84L3MBTL1
SCHEMBL8432556 0.88 MAOB (0.40) MAOBFAAHMAOA
SCHEMBL7765461 0.88 KCNH2 (0.37) MAOBFAAHL3MBTL1
SCHEMBL8015048 0.88 MAOB (0.40) MAOBMAOAGPR84
SCHEMBL8015049 0.88 MAOB (0.40) MAOBMAOAGPR84
SCHEMBL7765458 0.88 KCNH2 (0.37) MAOBFAAHL3MBTL1
SCHEMBL7765453 0.88 KCNH2 (0.37) MAOBFAAHL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0692485-B1 Cyclohexane carbaldehyde compounds and processes for preparing silacyclohexane-based liquid crystal compounds from the carbaldehyde compound SHINETSU CHEMICAL CO (JP) 2000-01-05 EP disclosed
US-5519156-A Cyclohexane carbaldehyde compounds and processes for preparing silacyclohexane-based liquid crystal compounds from the carbaldehyde SHIN-ETSU CHEMICAL CO., LTD. (JP) 1996-05-21 US disclosed
EP-0692485-A1 Cyclohexane carbaldehyde compounds and processes for preparing silacyclohexane-based liquid crystal compounds from the carbaldehyde compound Shin-Etsu Chemical Co., Ltd. (JP) 1996-01-17 EP disclosed