Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 2/20 | 0.36 |
| ▸ | GID4 | Q8IVV7 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.33 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.33 |
| ▸ | TAOK3 | Q9H2K8 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KCNN1 | Q92952 | 1/20 | 0.32 |
| ▸ | KCNN2 | Q9H2S1 | 1/20 | 0.32 |
| ▸ | KCNN3 | Q9UGI6 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19803966 | 0.78 | IGF1R (0.39) | IGF1RALOX15IDO1GID4MEN1 | |
| SCHEMBL1941577 | 0.78 | IGF1R (0.39) | IGF1RALOX15IDO1GID4MEN1 | |
| SCHEMBL6811001 | 0.78 | IGF1R (0.42) | IGF1RALOX15IDO1TSHR | |
| SCHEMBL1941083 | 0.78 | IGF1R (0.39) | IGF1RALOX15IDO1GID4MEN1 | |
| SCHEMBL466344 | 0.76 | IDO1 (0.53) | IDO1MEN1KMT2ATSHR | |
| SCHEMBL10876535 | 0.75 | IGF1R (0.37) | IGF1RALOX15IDO1GID4PFKFB3 | |
| SCHEMBL1942800 | 0.74 | IGF1R (0.36) | IGF1RALOX15IDO1MEN1KMT2A | |
| SCHEMBL27502261 | 0.74 | HTR6 (0.37) | IGF1RALOX15IDO1GID4MEN1 | |
| SCHEMBL322019 | 0.74 | HTR6 (0.39) | HTR6 | |
| SCHEMBL6406283 | 0.74 | IGF1R (0.37) | IGF1RALOX15HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0808839-B1 | EPOXYSUCCINAMIDE DERIVATIVES OR SALTS THEREOF, AND DRUGS CONTAINING THE SAME | TAIHO PHARMACEUTICAL CO LTD (JP) | 2001-05-23 | — | — | EP | disclosed |
| US-5883121-A | INHIBITING ACTIVITY AGAINST CATHEPSIN, AND IS USEFUL FOR PREVENTION AND TREATMENT OF OSTEOPATHY SUCH AS OSTEOPOROSIS | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 1999-03-16 | — | — | US | disclosed |
| EP-0808839-A1 | EPOXYSUCCINAMIDE DERIVATIVES OR SALTS THEREOF, AND DRUGS CONTAINING THE SAME | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 1997-11-26 | — | — | EP | disclosed |