Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.59 |
| ▸ | NPC1 | O15118 | 4/20 | 0.59 |
| ▸ | RAB9A | P51151 | 4/20 | 0.59 |
| ▸ | MAPT | P10636 | 5/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | GLA | P06280 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | PARP1 | P09874 | 1/20 | 0.52 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.50 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.50 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.50 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.49 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.49 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.49 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7773565 | 0.99 | LMNA (0.61) | LMNAHPGDSMN1; SMN2NPC1RAB9A | |
| SCHEMBL7771348 | 0.96 | LMNA (0.64) | LMNAHPGDSMN1; SMN2NPC1RAB9A | |
| SCHEMBL7770821 | 0.86 | HPGD (0.68) | LMNAHPGDSMN1; SMN2NPC1RAB9A | |
| SCHEMBL1260451 | 0.83 | HPGD (0.60) | LMNAHPGDSMN1; SMN2NPC1RAB9A | |
| SCHEMBL7180401 | 0.81 | HPGD (0.72) | LMNAHPGDSMN1; SMN2NPC1RAB9A | |
| SCHEMBL7769596 | 0.81 | LMNA (0.63) | LMNAHPGDSMN1; SMN2NPC1RAB9A | |
| SCHEMBL7765749 | 0.81 | HPGD (0.63) | LMNAHPGDSMN1; SMN2NPC1RAB9A | |
| SCHEMBL7765642 | 0.79 | HPGD (0.60) | LMNAHPGDSMN1; SMN2NPC1RAB9A | |
| SCHEMBL10762816 | 0.78 | S1PR1 (0.58) | NPC1RAB9AMEN1KMT2AS1PR1 | |
| SCHEMBL11747076 | 0.78 | S1PR1 (0.53) | SMN1; SMN2RAB9AALDH1A1PKMS1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0755927-B1 | DIMETHYLFURANCARBOXANILIDE DERIVATIVE | SANKYO CO (JP) | 2001-07-18 | — | — | EP | disclosed |