Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR3 | Q9UBY5 | 5/20 | 0.34 |
| ▸ | LPAR2 | Q9HBW0 | 4/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.31 |
| ▸ | CA1 | P00915 | 7/20 | 0.31 |
| ▸ | CA2 | P00918 | 7/20 | 0.31 |
| ▸ | CA9 | Q16790 | 7/20 | 0.31 |
| ▸ | THRB | P10828 | 2/20 | 0.31 |
| ▸ | CA12 | O43570 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.30 |
| ▸ | NAAA | Q02083 | 1/20 | 0.30 |
| ▸ | CA3 | P07451 | 1/20 | 0.30 |
| ▸ | CA4 | P22748 | 1/20 | 0.30 |
| ▸ | CA6 | P23280 | 1/20 | 0.30 |
| ▸ | CA5A | P35218 | 1/20 | 0.30 |
| ▸ | CA7 | P43166 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7763402 | 0.98 | LPAR3 (0.38) | LPAR3LPAR2TSHRCA1CA2 | |
| SCHEMBL7629081 | 0.98 | LPAR3 (0.38) | LPAR3LPAR2TSHRCA1CA2 | |
| SCHEMBL7765878 | 0.98 | LPAR3 (0.38) | LPAR3LPAR2TSHRCA1CA2 | |
| SCHEMBL2125841 | 0.93 | ADRB2 (0.35) | TSHR | |
| SCHEMBL7768011 | 0.89 | CA1 (0.34) | LPAR3LPAR2TSHRCA1CA2 | |
| SCHEMBL7763412 | 0.87 | CA1 (0.33) | LPAR3LPAR2TSHRCA1CA2 | |
| SCHEMBL7764806 | 0.87 | CA1 (0.36) | LPAR3LPAR2TSHRCA1CA2 | |
| SCHEMBL7768005 | 0.87 | CA1 (0.36) | LPAR3LPAR2TSHRCA1CA2 | |
| SCHEMBL7764781 | 0.87 | CA1 (0.36) | LPAR3LPAR2TSHRCA1CA2 | |
| SCHEMBL7768042 | 0.85 | CA1 (0.35) | LPAR3LPAR2TSHRCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0705838-B1 | Process for the preparation of silane polysulfides | CROMPTON CORP (US) | 2001-05-23 | — | — | EP | disclosed |
| US-5596116-A | Process for the preparation of silane polysulfides | OSI SPECIALTIES, INC. (US) | 1997-01-21 | — | — | US | disclosed |
| EP-0705838-A2 | Process for the preparation of silane polysulfides | OSi SPECIALTIES, INC. (US) | 1996-04-10 | — | — | EP | disclosed |
| US-5489701-A | REACTING SULFUR AND A HALOHYDROCARBYLALKOXYSILANE WITH THE REACTION PRODUCT OF HYDROGEN SULFIDE GAS AND A METAL ALKOXIDE SOLUTION | OSI SPECIALTIES, INC. (US) | 1996-02-06 | — | — | US | disclosed |
| US-5466848-A | Sulfiding sodium ethoxide with hydrogen sulfide to make sodium sulfide; reacting with sulfur to tetrasulfide; reacting with halohydrocarbylalkoxysilane | OSI SPECIALTIES, INC. (US) | 1995-11-14 | — | — | US | disclosed |