Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 2/20 | 0.46 |
| ▸ | MMP9 | P14780 | 2/20 | 0.46 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.42 |
| ▸ | MMP3 | P08254 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.38 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7764881 | 1.00 | MMP1 (0.46) | MMP1MMP9CRBNMEN1KMT2A | |
| SCHEMBL7762208 | 1.00 | MMP1 (0.46) | MMP1MMP9CRBNMEN1KMT2A | |
| SCHEMBL7765779 | 0.92 | CRBN (0.40) | MMP1MMP9CRBNMEN1KMT2A | |
| SCHEMBL7764867 | 0.89 | MEN1 (0.40) | MMP1MMP9CRBNMEN1KMT2A | |
| SCHEMBL7762226 | 0.83 | CRBN (0.40) | MMP1MMP9CRBNMEN1KMT2A | |
| SCHEMBL7764893 | 0.82 | CRBN (0.36) | MMP1MMP9CRBNMEN1KMT2A | |
| SCHEMBL7769377 | 0.79 | CRBN (0.39) | MMP1MMP9CRBNMEN1KMT2A | |
| SCHEMBL7765650 | 0.77 | MEN1 (0.45) | MMP1MMP9MEN1KMT2AALDH1A1 | |
| SCHEMBL7762198 | 0.75 | CRBN (0.39) | MMP1MMP9CRBNMEN1KMT2A | |
| SCHEMBL7767479 | 0.75 | CRBN (0.39) | MMP1MMP9CRBNMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0639566-B1 | CYCLIC COMPOUND | SANTEN PHARMACEUTICAL CO LTD (JP) | 2001-06-20 | — | — | EP | disclosed |
| US-5461158-A | Immunodeficiency and autoimmune diseases | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1995-10-24 | — | — | US | disclosed |
| EP-0639566-A1 | CYCLIC COMPOUND | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1995-02-22 | — | — | EP | disclosed |