Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | MAPT | P10636 | 2/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.62 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.62 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.62 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.62 |
| ▸ | HTR2B | P41595 | 1/20 | 0.62 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.62 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 5/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8799353 | 0.93 | LMNA (0.72) | LMNACYP3A4KMT2AMAPTMEN1 | |
| SCHEMBL9245529 | 0.93 | LMNA (0.72) | LMNACYP3A4KMT2AMAPTMEN1 | |
| SCHEMBL9080440 | 0.93 | LMNA (0.72) | LMNACYP3A4KMT2AMAPTMEN1 | |
| SCHEMBL6709213 | 0.91 | LMNA (0.55) | LMNACYP3A4KMT2AMAPTMEN1 | |
| SCHEMBL9898531 | 0.86 | LMNA (0.66) | LMNACYP3A4KMT2AMAPTMEN1 | |
| SCHEMBL975212 | 0.85 | TSHR (0.77) | LMNACYP3A4KMT2AMAPTMEN1 | |
| SCHEMBL301123 | 0.84 | KMT2A (0.69) | LMNACYP3A4KMT2AMAPTMEN1 | |
| SCHEMBL29994009 | 0.84 | KMT2A (0.69) | LMNACYP3A4KMT2AMAPTMEN1 | |
| SCHEMBL8154526 | 0.84 | LMNA (0.74) | LMNACYP3A4KMT2AMAPTMEN1 | |
| SCHEMBL50006 | 0.84 | LMNA (0.64) | LMNACYP3A4KMT2AMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5409808-A | Excellent sensitivity and gradation; improved storage stability | FUJI PHOTO FILM CO., LTD. (JP) | 1995-04-25 | — | — | US | claimed |
| US-6331628-B1 | REACTING A SUBSTITUTED HALOBENZENE WITH POTASSIUM, SODIUM AND/OR ZINC CYANIDE IN THE PRESENCE OF A METALLIC CATALYST | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2001-12-18 | — | — | US | disclosed |
| EP-0765879-B1 | 13-Substituted milbemycin 5-oxime derivatives, their preparation and their use against insects and other pests | SANKYO CO (JP) | 2001-02-14 | — | — | EP | disclosed |
| US-5861429-A | MITICIDES AND ANTHELMINTICS | SANKYO COMPANY, LIMITED (JP) | 1999-01-19 | — | — | US | disclosed |
| EP-0765879-A1 | 13-Substituted milbemycin 5-oxime derivatives, their preparation and their use against insects and other pests | SANKYO COMPANY LIMITED (JP) | 1997-04-02 | — | — | EP | disclosed |
| US-5409808-A | Excellent sensitivity and gradation; improved storage stability | FUJI PHOTO FILM CO., LTD. (JP) | 1995-04-25 | — | — | US | disclosed |