Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 13/20 | 0.44 |
| ▸ | SPHK2 | Q9NRA0 | 7/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TYR | P14679 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | RARB | P10826 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7764931 | 1.00 | SPHK1 (0.44) | SPHK1SPHK2FFAR4MEN1TP53 | |
| SCHEMBL7761160 | 1.00 | SPHK1 (0.44) | SPHK1SPHK2FFAR4MEN1TP53 | |
| SCHEMBL7764646 | 1.00 | SPHK1 (0.44) | SPHK1SPHK2FFAR4MEN1TP53 | |
| SCHEMBL7765179 | 1.00 | SPHK1 (0.44) | SPHK1SPHK2FFAR4MEN1TP53 | |
| SCHEMBL7768268 | 1.00 | SPHK1 (0.44) | SPHK1SPHK2FFAR4MEN1TP53 | |
| SCHEMBL7766115 | 1.00 | SPHK1 (0.44) | SPHK1SPHK2FFAR4MEN1TP53 | |
| SCHEMBL7766082 | 0.99 | SPHK1 (0.42) | SPHK1SPHK2FFAR4RARB | |
| SCHEMBL7763778 | 0.95 | SPHK1 (0.37) | SPHK1SPHK2FFAR4 | |
| SCHEMBL7761135 | 0.90 | CTSL (0.36) | SPHK1FFAR4CYP3A4 | |
| SCHEMBL9406065 | 0.88 | SPHK1 (0.42) | SPHK1SPHK2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0781827-B1 | Liquid crystal mixture and liquid crystal device comprising the same | SUMITOMO CHEMICAL CO (JP) | 2001-06-13 | — | — | EP | disclosed |
| US-6149837-A | SUBSTITUTED 1,4-BIS(SUBSTITUED PHENYLACETYLENE)BENZENE WHERE AT LEAST ONE RING HAS AN ALKYL ATTACHMENT, HAS A LARGE ANISOTROPY OF REFRACTIVE INDEX, TENDS TO BE MIXED WITH OTHER LIQUID CRYSTALS, IS LIGHT STABLE; LIQUID CRYSTAL ELEMENT | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-11-21 | — | — | US | disclosed |
| US-5866035-A | LARGE BIREFRINGENCE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1999-02-02 | — | — | US | disclosed |
| EP-0781827-A1 | Liquid crystal mixture and liquid crystal device comprising the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-02 | — | — | EP | disclosed |