Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NMBR | P28336 | 2/20 | 0.62 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.56 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.56 |
| ▸ | ITGAL | P20701 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | MPO | P05164 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | BLM | P54132 | 1/20 | 0.56 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.56 |
| ▸ | ACE | P12821 | 3/20 | 0.56 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | MMP2 | P08253 | 1/20 | 0.54 |
| ▸ | MMP9 | P14780 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7201043 | 0.90 | KDM4E (0.61) | ALOX15ITGB2ICAM1ITGALMEN1 | |
| SCHEMBL8384762 | 0.88 | MEN1 (0.62) | ALOX15ITGB2ICAM1ITGALMEN1 | |
| SCHEMBL6245120 | 0.88 | MEN1 (0.62) | ALOX15ITGB2ICAM1ITGALMEN1 | |
| SCHEMBL8384759 | 0.88 | MEN1 (0.62) | ALOX15ITGB2ICAM1ITGALMEN1 | |
| SCHEMBL6245123 | 0.88 | MEN1 (0.62) | ALOX15ITGB2ICAM1ITGALMEN1 | |
| SCHEMBL6244059 | 0.88 | MEN1 (0.62) | ALOX15ITGB2ICAM1ITGALMEN1 | |
| SCHEMBL6244061 | 0.88 | MEN1 (0.62) | ALOX15ITGB2ICAM1ITGALMEN1 | |
| SCHEMBL28377319 | 0.88 | MEN1 (0.62) | ALOX15ITGB2ICAM1ITGALMEN1 | |
| SCHEMBL31557352 | 0.88 | ALOX15 (0.59) | ALOX15ITGB2ICAM1ITGALMEN1 | |
| SCHEMBL28822323 | 0.87 | MEN1 (0.61) | ALOX15ITGB2ICAM1ITGALMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001088178-A2 | PEPTIDE SUBSTRATES FOR DIRECT MEASURING OF ENZYME ACTIVITIES | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2001-11-22 | — | — | WO | claimed |
| WO-2001088178-A2 | PEPTIDE SUBSTRATES FOR DIRECT MEASURING OF ENZYME ACTIVITIES | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2001-11-22 | — | — | WO | disclosed |