SCHEMBL7766732

SCHEMBL7766732

O=C(NC(CO)C(O)CO)c1c(I)c(CO)c(I)c(NC(=O)C(O)CC(O)CO)c1I

nearest known ligand 0.44

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.44
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7590127 0.91 LMNA (0.47) LMNASMN1; SMN2
SCHEMBL7595384 0.88 LMNA (0.44) LMNASMN1; SMN2
SCHEMBL7589582 0.86 LMNA (0.47) LMNASMN1; SMN2
SCHEMBL7591801 0.85 LMNA (0.62) LMNASMN1; SMN2
SCHEMBL7595621 0.83 LMNA (0.44) LMNASMN1; SMN2
SCHEMBL7590713 0.82 LMNA (0.42) LMNASMN1; SMN2
SCHEMBL7592512 0.77 LMNA (0.64) LMNASMN1; SMN2
SCHEMBL6226822 0.75 LMNA (0.46) LMNASMN1; SMN2
SCHEMBL8074434 0.74 LMNA (0.35) LMNA
SCHEMBL7592508 0.74 LMNA (0.60) LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5993780-A A POLYIODOARYLALKYL ALCOHOL OR DERIVATIVE NYCOMED IMAGING AS (NO) 1999-11-30 US claimed
US-6310243-B1 BENZENE COMPOUNDS IN WHICH 3 NON-ADJACENT RING ATOMS ARE SUBSTITUTED WITH IODINE, 2 OF THE REMAINING RING ATOMS ARE AMIDE SUBSTITUTED WITH HYDROXY AND THE OTHER REMAINING RING ATOM IS A NON-AMIDE, HYDROXY-SUBSTITUTED NONIONIC MOIETY NYCOMED IMAGING AS (NO) 2001-10-30 US disclosed
US-5993780-A A POLYIODOARYLALKYL ALCOHOL OR DERIVATIVE NYCOMED IMAGING AS (NO) 1999-11-30 US disclosed