SCHEMBL7766802

SCHEMBL7766802

CC[Si](CC)=[Zr](C)(C)(C1C=Cc2ccccc21)C1C=Cc2ccccc21

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 2/20 0.38
KDM4E B2RXH2 2/20 0.35
LMNA P02545 1/20 0.35
TP53 P04637 1/20 0.35
CHRM2 P08172 1/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2D6 P10635 1/20 0.35
CHRM1 P11229 1/20 0.35
DRD2 P14416 1/20 0.35
ADRA2B P18089 1/20 0.35
ADRA2C P18825 1/20 0.35
NFKB1 P19838 1/20 0.35
CHRM3 P20309 1/20 0.35
SLC6A2 P23975 1/20 0.35
HTR2C P28335 1/20 0.35
ADRA1A P35348 1/20 0.35
HRH1 P35367 1/20 0.35
DRD3 P35462 1/20 0.35
THPO P40225 1/20 0.35
OPRK1 P41145 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7643746 0.82 HTR2A (0.37) HTR2AKDM4ELMNATP53CHRM2
SCHEMBL6857144 0.81 HTR2A (0.37) HTR2AKDM4ELMNATP53CHRM2
SCHEMBL28440009 0.77 HTR2A (0.37) HTR2AKDM4ELMNATP53CHRM2
SCHEMBL1625095 0.77 HTR2A (0.34) HTR2AKDM4ELMNATP53CHRM2
SCHEMBL28670525 0.76 HTR2A (0.38) HTR2AKDM4ELMNATP53CHRM2
SCHEMBL30577433 0.76 HTR2A (0.40) HTR2AKDM4ELMNATP53CHRM2
SCHEMBL7632416 0.75 HTR2A (0.39) HTR2AKDM4ELMNATP53CHRM2
SCHEMBL7642384 0.74 RET (0.36) HTR2AKDM4ELMNATP53CHRM2
SCHEMBL7774282 0.73 HTR2A (0.38) HTR2AKDM4ELMNATP53CHRM2
Hydrochloric Acid SCHEMBL437853 0.73 HTR2A (0.34) HTR2AKDM4ELMNATP53CHRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0678530-B1 Process for production of cyclic olefin copolymers and copolymers produced by said process MITSUI CHEMICALS INC (JP) 2001-07-25 EP disclosed
EP-0719803-B1 Process for the production of cycloolefin random copolymer MITSUI CHEMICALS INC (JP) 2001-03-21 EP disclosed
US-5650471-A COPOLYMERIZING AN ALPHA-OLEFIN AND A CYCLOOLEFIN IN THE PRESENCE OF A CATALYST FORMED FROM A TRANSITION METAL COMPOUND AND AN ORGANIC ALUMINUM COMPOUND MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1997-07-22 US disclosed
US-5559199-A MOLECULAR WEIGHT CONTROL MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1996-09-24 US disclosed
EP-0729983-A2 Process for the production of cycloolefin random copolymer MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1996-09-04 EP disclosed
EP-0719803-A2 Process for the production of cycloolefin random copolymer MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1996-07-03 EP disclosed
EP-0678530-A1 Process for production of cyclic olefin copolymers and copolymers produced by said process MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1995-10-25 EP disclosed