SCHEMBL1625095

SCHEMBL1625095

C[Zr](C)(C1C=Cc2ccccc21)(C1C=Cc2ccccc21)=[Si](c1ccccc1)c1ccccc1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 2/20 0.34
SIGMAR1 Q99720 6/20 0.32
KDM4E B2RXH2 2/20 0.32
LMNA P02545 1/20 0.32
TP53 P04637 1/20 0.32
CHRM2 P08172 1/20 0.32
CYP3A4 P08684 1/20 0.32
CYP2D6 P10635 1/20 0.32
CHRM1 P11229 1/20 0.32
DRD2 P14416 1/20 0.32
ADRA2B P18089 1/20 0.32
ADRA2C P18825 1/20 0.32
NFKB1 P19838 1/20 0.32
CHRM3 P20309 1/20 0.32
SLC6A2 P23975 1/20 0.32
HTR2C P28335 1/20 0.32
ADRA1A P35348 1/20 0.32
HRH1 P35367 1/20 0.32
DRD3 P35462 1/20 0.32
THPO P40225 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6857144 0.81 HTR2A (0.37) HTR2ASIGMAR1KDM4ELMNATP53
SCHEMBL8755300 0.80 HTR2A (0.34) HTR2AHTR6
SCHEMBL547453 0.80 HTR2A (0.34) HTR2AHTR6
SCHEMBL8754873 0.79 HTR2A (0.33) HTR2AHTR6
SCHEMBL8754920 0.77 HTR2A (0.30) HTR2A
SCHEMBL7766802 0.77 HTR2A (0.38) HTR2ASIGMAR1KDM4ELMNATP53
SCHEMBL28670525 0.76 HTR2A (0.38) HTR2ASIGMAR1KDM4ELMNATP53
SCHEMBL8755140 0.75 SIGMAR1 (0.35) HTR2ASIGMAR1HTR6
SCHEMBL618391 0.74 HTR6 (0.33) HTR2ASIGMAR1KDM4ELMNATP53
SCHEMBL7061981 0.74 SIGMAR1 (0.34) HTR2ASIGMAR1KDM4ELMNATP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240228682-A1 POLYETHYLENE COPOLYMER WITH BROAD SHORT CHAIN BRANCHING DISTRIBUTION W.R. GRACE & CO.-CONN. (US) 2024-07-11 US disclosed
EP-4337703-A1 POLYETHYLENE COPOLYMER WITH BROAD SHORT CHAIN BRANCHING DISTRIBUTION W. R. Grace & Co.-Conn (US) 2024-03-20 EP disclosed
WO-2022241225-A1 POLYETHYLENE COPOLYMER WITH BROAD SHORT CHAIN BRANCHING DISTRIBUTION W.R. GRACE & CO.-CONN. (US) 2022-11-17 WO disclosed
EP-2099832-B1 CATALYST ACTIVATORS, PROCESSES FOR MAKING SAME, AND USE THEREOF IN CATALYSTS AND POLYMERIZATION OF OLEFINS GRACE W R & CO (US) 2019-03-27 EP disclosed
EP-2041188-B1 CATALYST ACTIVATORS, PROCESSES FOR MAKING SAME, AND USE THEREOF IN CATALYSTS AND POLYMERIZATION OF OLEFINS ALBEMARLE CORP (US) 2017-06-14 EP disclosed
EP-2195112-B1 ALUMINOXANE CATALYST ACTIVATORS DERIVED FROM DIALKYLALUMINUM CATION PRECURSOR AGENTS AND USE THEREOF IN CATALYSTS AND POLYMERIZATION OF OLEFINS ALBEMARLE CORP (US) 2017-03-01 EP disclosed
EP-2099833-B1 CATALYST ACTIVATORS, PROCESSES FOR MAKING SAME, AND USE THEREOF IN CATALYSTS AND POLYMERIZATION OF OLEFINS ALBEMARLE CORP (US) 2015-11-11 EP disclosed
US-9090720-B2 Aluminoxane catalyst activators containing carbocation agents, and use thereof in polyolefin catalysts ALBEMARLE CORPORATION (US) 2015-07-28 US disclosed
EP-2683749-A1 ALUMINOXANE CATALYST ACTIVATORS CONTAINING CARBOCATION AGENTS, AND USE THEREOF IN POLYOLEFIN CATALYSTS Albemarle Corporation (US) 2014-01-15 EP disclosed
US-20130345376-A1 Aluminoxane Catalyst Activators Containing Carbocation Agents, and use thereof in Polyolefin Catalysts ALBEMARLE CORPORATION (US) 2013-12-26 US disclosed
EP-2041189-A2 CATALYST ACTIVATORS, PROCESSES FOR MAKING SAME, AND USE THEREOF IN CATALYSTS AND POLYMERIZATION OF OLEFINS Albermarle Corporation (US) 2009-04-01 EP disclosed
WO-2009029857-A1 ALUMINOXANE CATALYST ACTIVATORS DERIVED FROM DIALKYLALUMINUM CATION PRECURSOR AGENTS, PROCESSES FOR MAKING SAME, AND USE THEREOF IN CATALYSTS AND POLYMERIZATION OF OLEFINS ALBEMARLE CORPORATION (US) 2009-03-05 WO disclosed
US-20090062492-A1 Aluminoxane Catalyst Activators Derived From Dialkylaluminum Cation Precursor Agents, Processes For Making Same, And Use Thereof In Catalysts And Polymerization Of Olefins ALBEMARLE CORPORATION (US) 2009-03-05 US disclosed
US-20080300372-A1 Catalyst Activators, Processes for Making Same, and Use Thereof in Catalysts and Polymerization of Olefins ALBEMARLE CORPORATION 2008-12-04 US disclosed
WO-2008076632-A2 CATALYST ACTIVATORS, PROCESSES FOR MAKING SAME, AND USE THEREOF IN CATALYSTS AND POLYMERIZATION OF OLEFINS ALBEMARLE CORPORATION (US) 2008-06-26 WO disclosed
WO-2008036594-A2 CATALYST ACTIVATORS, PROCESSES FOR MAKING SAME, AND USE THEREOF IN CATALYSTS AND POLYMERIZATION OF OLEFINS ALBEMARLE CORPORATION (US) 2008-03-27 WO disclosed
WO-2008036591-A2 CATALYST ACTIVATORS, PROCESSES FOR MAKING SAME, AND USE THEREOF IN CATALYSTS AND POLYMERIZATION OF OLEFINS ALBEMARLE CORPORATION (US) 2008-03-27 WO disclosed
WO-2008011267-A2 CATALYST ACTIVATORS, PROCESSES FOR MAKING SAME, AND USE THEREOF IN CATALYSTS AND POLYMERIZATION OF OLEFINS ALBEMARLE CORPORATION (US) 2008-01-24 WO disclosed
WO-2008011269-A2 CATALYST ACTIVATORS, PROCESSES FOR MAKING SAME, AND USE THEREOF IN CATALYSTS AND POLYMERIZATION OF OLEFINS ALBEMARLE CORPORATION (US) 2008-01-24 WO disclosed
EP-0768320-A1 Catalyst component and catalyst NIPPON OIL CO. LTD. (JP) 1997-04-16 EP disclosed