SCHEMBL7767084

SCHEMBL7767084

CCCCC[Si@H]1CC[C@H]([C@H]2CC[C@H](CCCCc3cc(F)c(F)c(F)c3)CC2)CC1

nearest known ligand 0.32

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ITGB3 P05106 1/20 0.32
ITGA2B P08514 1/20 0.32
OPRM1 P35372 1/20 0.31
PTGS2 P35354 3/20 0.31
CYP3A4 P08684 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7767080 1.00 ITGB3 (0.32) ITGB3ITGA2BOPRM1PTGS2CYP3A4
SCHEMBL7767087 1.00 ITGB3 (0.32) ITGB3ITGA2BOPRM1PTGS2CYP3A4
SCHEMBL7756467 0.93
SCHEMBL8453272 0.93
SCHEMBL7756462 0.93
SCHEMBL7769774 0.93 ITGB3 (0.34) ITGB3ITGA2BOPRM1PTGS2CYP3A4
SCHEMBL7769778 0.93 ITGB3 (0.34) ITGB3ITGA2BOPRM1PTGS2CYP3A4
SCHEMBL7767953 0.90 DAO (0.32) ITGB3ITGA2B
SCHEMBL7767955 0.90 DAO (0.32) ITGB3ITGA2B
SCHEMBL7767958 0.90 DAO (0.32) ITGB3ITGA2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0727428-B1 Novel silacyclohexane compounds, preparation thereof, liquid crystal compositions comprising the same, and liquid crystal devices comprising the compositions SHINETSU CHEMICAL CO (JP) 2001-06-06 EP disclosed
US-5665271-A Silacyclohexane compounds, preparation thereof, liquid crystal compositions comprising the same, and liquid crystal devices comprising the compositions SHIN-ETSU CHEMICAL CO., LTD. (JP) 1997-09-09 US disclosed
EP-0727428-A1 Novel silacyclohexane compounds, preparation thereof, liquid crystal compositions comprising the same, and liquid crystal devices comprising the compositions SHIN-ETSU CHEMICAL CO., LTD. (JP) 1996-08-21 EP disclosed