SCHEMBL7767103

SCHEMBL7767103

OP(O)Oc1ccccc1.[Ni]

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 4/20 0.43
TSHR P16473 1/20 0.43
CA5A P35218 1/20 0.40
CA5B Q9Y2D0 1/20 0.40
CA4 P22748 1/20 0.39
NR1H2 P55055 1/20 0.39
BAX Q07812 1/20 0.39
ALDH1A1 P00352 1/20 0.37
RECQL P46063 1/20 0.37
SRC P12931 1/20 0.37
KCNA3 P22001 1/20 0.36
ALOX15 P16050 1/20 0.36
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34
IDO1 P14902 1/20 0.33
LMNA P02545 1/20 0.33
MAOA P21397 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
HPGD P15428 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL126344 0.97 LTA4H (0.45) LTA4HTSHRCA5ACA5BCA4
SCHEMBL30275406 0.97 LTA4H (0.45) LTA4HTSHRCA5ACA5BCA4
SCHEMBL11444642 0.94 LTA4H (0.43) LTA4HTSHRCA5ACA5BCA4
Hydrochloric Acid SCHEMBL11619305 0.94 LTA4H (0.43) LTA4HTSHRCA5ACA5BCA4
SCHEMBL3257308 0.94 LTA4H (0.43) LTA4HTSHRCA5ACA5BCA4
SCHEMBL23754601 0.94 LTA4H (0.43) LTA4HTSHRCA5ACA5BCA4
SCHEMBL4585566 0.94 LTA4H (0.43) LTA4HTSHRCA5ACA5BCA4
SCHEMBL1160536 0.94 LTA4H (0.43) LTA4HTSHRCA5ACA5BCA4
Fluoride SCHEMBL2680499 0.94 LTA4H (0.43) LTA4HTSHRCA5ACA5BCA4
SCHEMBL3248793 0.94 LTA4H (0.43) LTA4HTSHRCA5ACA5BCA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0417325-B1 PROCESS FOR PRODUCING NORCAMPHANEDICARBONITRILES MITSUI CHEMICALS INC (JP) 2001-07-11 EP claimed
US-5169971-A Hydrocyanation; zero-valent nickel complex catalyst and a lewis acid; efficient; high selectivity MITSUI TOATSU CHEMICALS, INC. (JP) 1992-12-08 US claimed
EP-0417325-A1 PROCESS FOR PRODUCING NORCAMPHANEDICARBONITRILES MITSUI TOATSU CHEMICALS, Inc. (JP) 1991-03-20 EP claimed
EP-0417325-B1 PROCESS FOR PRODUCING NORCAMPHANEDICARBONITRILES MITSUI CHEMICALS INC (JP) 2001-07-11 EP disclosed
EP-0438638-B1 Process for producing norcamphane dicarbonitriles MITSUI CHEMICALS INC (JP) 2000-07-05 EP disclosed
US-5169971-A Hydrocyanation; zero-valent nickel complex catalyst and a lewis acid; efficient; high selectivity MITSUI TOATSU CHEMICALS, INC. (JP) 1992-12-08 US disclosed
US-5087722-A Catalytic hydrocyanation of bicyclo(2.2.1)-5-heptene-2-carbonitrile MITSUI TOATSU CHEMICALS, INC. (JP) 1992-02-11 US disclosed
EP-0438638-A1 Process for producing norcamphane dicarbonitriles MITSUI TOATSU CHEMICALS, Inc. (JP) 1991-07-31 EP disclosed
EP-0417325-A1 PROCESS FOR PRODUCING NORCAMPHANEDICARBONITRILES MITSUI TOATSU CHEMICALS, Inc. (JP) 1991-03-20 EP disclosed