Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 4/20 | 0.49 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | MAPKAPK2 | P49137 | 2/20 | 0.34 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | MMP13 | P45452 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | OGA | O60502 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20873175 | 0.85 | NPSR1 (0.39) | MEN1KMT2ANPSR1 | |
| SCHEMBL3288030 | 0.82 | SMN1; SMN2 (0.43) | MEN1KMT2A | |
| SCHEMBL1134230 | 0.82 | SMN1; SMN2 (0.43) | MEN1KMT2A | |
| SCHEMBL6832915 | 0.78 | SMN1; SMN2 (0.40) | MEN1KMT2ARAB9A | |
| SCHEMBL4061370 | 0.74 | ELANE (0.81) | ELANEKDM1AMAPKAPK2MEN1KMT2A | |
| SCHEMBL13645108 | 0.74 | ELANE (0.64) | ELANEKDM1AMAPKAPK2MEN1KMT2A | |
| SCHEMBL1642844 | 0.73 | CYP2B6 (0.41) | NPSR1 | |
| SCHEMBL2171679 | 0.73 | AAK1 (0.38) | MEN1KMT2A | |
| SCHEMBL7106522 | 0.71 | ELANE (0.55) | ELANEKDM1A | |
| SCHEMBL4056333 | 0.70 | ELANE (0.64) | ELANEKDM1AMEN1KMT2ACA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0820438-B1 | O-CARBAMOYL-PHENYLALANINOL HAVING SUBSTITUENT AT BENZENE RING, ITS PHARMACEUTICALLY USEFUL SALTS AND METHOD FOR PREPARING THE SAME | SK CORP (KR) | 2001-06-20 | — | — | EP | disclosed |
| US-6140532-A | O-carbamoyl-phenylalaninol having substituent at benzene ring, its pharmaceutically useful salts and method for preparing the same | SK CORPORATION (US) | 2000-10-31 | — | — | US | disclosed |