Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 17/20 | 0.84 |
| ▸ | DRD3 | P35462 | 17/20 | 0.84 |
| ▸ | DRD4 | P21917 | 10/20 | 0.84 |
| ▸ | HTR1A | P08908 | 5/20 | 0.84 |
| ▸ | HTR2A | P28223 | 5/20 | 0.84 |
| ▸ | HTR2C | P28335 | 4/20 | 0.84 |
| ▸ | MEN1 | O00255 | 1/20 | 0.84 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.84 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7762559 | 0.99 | DRD2 (0.82) | DRD2DRD3DRD4HTR1AHTR2A | |
| SCHEMBL7769911 | 0.93 | DRD2 (0.90) | DRD2DRD3DRD4HTR1AHTR2A | |
| SCHEMBL7769974 | 0.92 | DRD2 (0.76) | DRD2DRD3DRD4HTR1AHTR2A | |
| Hydrochloric Acid SCHEMBL7766169 | 0.92 | DRD2 (0.88) | DRD2DRD3DRD4HTR1AHTR2A | |
| SCHEMBL7762650 | 0.91 | DRD3 (1.00) | DRD2DRD3DRD4HTR1AHTR2A | |
| Hydrochloric Acid SCHEMBL7766165 | 0.91 | DRD2 (0.75) | DRD2DRD3DRD4HTR1AHTR2A | |
| Hydrochloric Acid SCHEMBL7762562 | 0.90 | DRD3 (0.98) | DRD2DRD3DRD4HTR1AHTR2A | |
| Hydrochloric Acid SCHEMBL29407111 | 0.90 | DRD3 (0.98) | DRD2DRD3DRD4HTR1AHTR2A | |
| SCHEMBL7769531 | 0.88 | DRD2 (0.79) | DRD2DRD3DRD4HTR1AHTR2A | |
| Hydrochloric Acid SCHEMBL7767949 | 0.88 | DRD2 (0.77) | DRD2DRD3DRD4HTR1AHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0873329-B1 | NOVEL N-AMINOALKYLFLUORENECARBOXAMIDES; A NEW CLASS OF DOPAMINE RECEPTOR SUBTYPE SPECIFIC LIGANDS | NEUROGEN CORP (US) | 2001-06-06 | — | — | EP | claimed |