Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.32 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7761314 | 0.79 | TAAR1 (0.42) | MAPTKMT2AMAPK1HTTNPSR1 | |
| SCHEMBL7766037 | 0.75 | AAK1 (0.46) | MAPTMAPK1HTT | |
| SCHEMBL3800127 | 0.74 | MAPT (0.45) | MAPTKMT2AMAPK1HTTNPSR1 | |
| SCHEMBL8453893 | 0.74 | SCN9A (0.44) | LMNATSHRSCN9ASCN5A | |
| SCHEMBL31168037 | 0.74 | SOD1 (0.39) | — | |
| SCHEMBL7769819 | 0.73 | MAPT (0.42) | MAPTKMT2AMAPK1HTTNPSR1 | |
| SCHEMBL4550768 | 0.73 | SCN5A (0.34) | MAPTKMT2ANPSR1LMNATSHR | |
| SCHEMBL28389420 | 0.72 | — | — | |
| SCHEMBL7765182 | 0.72 | MAPT (0.41) | MAPTKMT2AMAPK1HTTNPSR1 | |
| Hydrochloric Acid SCHEMBL2716655 | 0.72 | MAPT (0.35) | MAPTKMT2AMAPK1HTTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0727428-B1 | Novel silacyclohexane compounds, preparation thereof, liquid crystal compositions comprising the same, and liquid crystal devices comprising the compositions | SHINETSU CHEMICAL CO (JP) | 2001-06-06 | — | — | EP | disclosed |
| US-6159393-A | Benzene derivatives and liquid-crystalline medium | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2000-12-12 | — | — | US | disclosed |
| EP-0775101-B1 | BENZENE DERIVATIVES AND LIQUID CRYSTAL MEDIUM | MERCK PATENT GMBH (DE) | 2000-05-03 | — | — | EP | disclosed |
| US-5665271-A | Silacyclohexane compounds, preparation thereof, liquid crystal compositions comprising the same, and liquid crystal devices comprising the compositions | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1997-09-09 | — | — | US | disclosed |
| EP-0775101-A1 | BENZENE DERIVATIVES AND LIQUID CRYSTAL MEDIUM | MERCK PATENT GmbH (DE) | 1997-05-28 | — | — | EP | disclosed |
| EP-0727428-A1 | Novel silacyclohexane compounds, preparation thereof, liquid crystal compositions comprising the same, and liquid crystal devices comprising the compositions | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1996-08-21 | — | — | EP | disclosed |
| WO-1996005159-A1 | BENZENE DERIVATIVES AND LIQUID CRYSTAL MEDIUM | MERCK PATENT GMBH (DE) | 1996-02-22 | — | — | WO | disclosed |
| US-5422035-A | Mixture of polar compounds free of nitrile-containing compounds havng a positive dielectric anisotropy; twisted and supertwisted nematic cells; high resistance; low voltage | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1995-06-06 | — | — | US | disclosed |