Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29046891 | 0.79 | MAPT (0.34) | MAPTKMT2ANPSR1MAPK1HTT | |
| SCHEMBL6684943 | 0.79 | MAPT (0.36) | MAPTKMT2ANPSR1MAPK1HTT | |
| SCHEMBL4680982 | 0.72 | MAPT (0.39) | MAPTKMT2ANPSR1MAPK1HTT | |
| SCHEMBL16335705 | 0.71 | MAPT (0.41) | MAPTKMT2ANPSR1MAPK1HTT | |
| SCHEMBL28460846 | 0.71 | MAPT (0.41) | MAPTKMT2ANPSR1MAPK1HTT | |
| SCHEMBL16334852 | 0.71 | MAPT (0.41) | MAPTKMT2ANPSR1MAPK1HTT | |
| SCHEMBL7767196 | 0.69 | MAPT (0.50) | MAPTKMT2ANPSR1MAPK1HTT | |
| SCHEMBL28457462 | 0.69 | MAPT (0.34) | MAPTKMT2ANPSR1MAPK1HTT | |
| SCHEMBL16334574 | 0.69 | MAPT (0.34) | MAPTKMT2ANPSR1MAPK1HTT | |
| SCHEMBL16334453 | 0.69 | MAPT (0.34) | MAPTKMT2ANPSR1MAPK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0727428-B1 | Novel silacyclohexane compounds, preparation thereof, liquid crystal compositions comprising the same, and liquid crystal devices comprising the compositions | SHINETSU CHEMICAL CO (JP) | 2001-06-06 | — | — | EP | disclosed |
| US-5665271-A | Silacyclohexane compounds, preparation thereof, liquid crystal compositions comprising the same, and liquid crystal devices comprising the compositions | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1997-09-09 | — | — | US | disclosed |
| EP-0727428-A1 | Novel silacyclohexane compounds, preparation thereof, liquid crystal compositions comprising the same, and liquid crystal devices comprising the compositions | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1996-08-21 | — | — | EP | disclosed |