SCHEMBL7767258

SCHEMBL7767258

CCCCc1cc(CC)ccc1OP(=O)(Oc1ccc(CC)cc1CCCC)Oc1ccc(CC)cc1CCCC

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKT1 P31749 1/20 0.39
HTT P42858 3/20 0.39
MAPT P10636 3/20 0.39
MAPK1 P28482 2/20 0.39
APAF1 O14727 2/20 0.39
THRB P10828 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
RAD52 P43351 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
NPC1 O15118 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
POLB P06746 2/20 0.35
KDM4E B2RXH2 2/20 0.35
ALDH1A1 P00352 1/20 0.35
LMNA P02545 1/20 0.35
BLM P54132 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
CYP2C19 P33261 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30692697 0.92 HTT (0.45) HTTMAPTMAPK1APAF1THRB
SCHEMBL1791071 0.92 HTT (0.45) HTTMAPTMAPK1APAF1THRB
SCHEMBL7767259 0.88 INPPL1 (0.43) AKT1HTTMAPTMAPK1APAF1
SCHEMBL6046755 0.87 AKT1 (0.41) AKT1HTTMAPTMAPK1L3MBTL1
SCHEMBL6478069 0.86 HTT (0.49) HTTMAPTMAPK1APAF1THRB
SCHEMBL30688987 0.80 HTT (0.43) HTTMAPTMAPK1APAF1THRB
SCHEMBL6480565 0.80 INPPL1 (0.44) AKT1HTTMAPTMAPK1APAF1
SCHEMBL28981562 0.80 HTT (0.43) HTTMAPTMAPK1APAF1THRB
SCHEMBL27778654 0.79 INPPL1 (0.43) AKT1HTTMAPTMAPK1APAF1
SCHEMBL3683525 0.77 MAPT (0.41) HTTMAPTMAPK1THRBL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1108733-A1 Propylene-ethylene block copolymer, resin composition, and blow-molded article IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2001-06-20 EP disclosed