Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | APAF1 | O14727 | 2/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | RAD52 | P43351 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1791071 | 0.94 | HTT (0.45) | HTTMAPTMAPK1APAF1THRB | |
| SCHEMBL30692697 | 0.94 | HTT (0.45) | HTTMAPTMAPK1APAF1THRB | |
| SCHEMBL7767258 | 0.86 | AKT1 (0.39) | HTTMAPTMAPK1APAF1THRB | |
| SCHEMBL3683525 | 0.85 | MAPT (0.41) | HTTMAPTMAPK1THRBL3MBTL1 | |
| SCHEMBL27472499 | 0.84 | ENPP2 (0.47) | HTTMAPTMAPK1APAF1THRB | |
| SCHEMBL28981562 | 0.82 | HTT (0.43) | HTTMAPTMAPK1APAF1THRB | |
| SCHEMBL30688987 | 0.82 | HTT (0.43) | HTTMAPTMAPK1APAF1THRB | |
| SCHEMBL6480565 | 0.82 | INPPL1 (0.44) | HTTMAPTMAPK1APAF1THRB | |
| SCHEMBL10690635 | 0.81 | HTT (0.46) | HTTMAPTMAPK1APAF1THRB | |
| SCHEMBL14122353 | 0.81 | PPARG (0.57) | HTTMAPTMAPK1APAF1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6846863-B2 | Polyethylene composition and method for making shaped objects from same | SOLVAY POLYOLEFINS EUROPE-BELGIUM (S.A.) (BE) | 2005-01-25 | — | — | US | disclosed |
| US-20030105198-A1 | Polyethylene composition and method for making shaped objects from same | INEOS USA LLC | 2003-06-05 | — | — | US | disclosed |