Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | RAD52 | P43351 | 1/20 | 0.44 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.44 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7767344 | 1.00 | EPHX1 (0.53) | EPHX1HDAC3HDAC1HDAC2RAD52 | |
| SCHEMBL7766373 | 0.95 | EPHX1 (0.56) | EPHX1HDAC3HDAC1HDAC2RAD52 | |
| SCHEMBL7766366 | 0.95 | EPHX1 (0.56) | EPHX1HDAC3HDAC1HDAC2RAD52 | |
| SCHEMBL7767350 | 0.91 | EPHX1 (0.52) | EPHX1HDAC3HDAC1HDAC2RAD52 | |
| SCHEMBL7762740 | 0.91 | EPHX1 (0.52) | EPHX1HDAC3HDAC1HDAC2RAD52 | |
| SCHEMBL7762734 | 0.91 | EPHX1 (0.52) | EPHX1HDAC3HDAC1HDAC2RAD52 | |
| SCHEMBL7767353 | 0.91 | EPHX1 (0.52) | EPHX1HDAC3HDAC1HDAC2RAD52 | |
| SCHEMBL7765462 | 0.81 | ALDH1A1 (0.55) | EPHX1SHMT2ATMALDH1A1KDM4E | |
| SCHEMBL7765465 | 0.81 | ALDH1A1 (0.55) | EPHX1SHMT2ATMALDH1A1KDM4E | |
| SCHEMBL7765470 | 0.81 | ALDH1A1 (0.55) | EPHX1SHMT2ATMALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0718281-B1 | CYCLOHEXANEDIUREA DERIVATIVE AND PROCESS FOR PRODUCING THE SAME | NISSIN FOOD PRODUCTS LTD (JP) | 2001-06-27 | — | — | EP | disclosed |
| EP-0718281-A1 | CYCLOHEXANEDIUREA DERIVATIVE AND PROCESS FOR PRODUCING THE SAME | NISSIN FOOD PRODUCTS CO., LTD. (JP) | 1996-06-26 | — | — | EP | disclosed |