SCHEMBL7767586

SCHEMBL7767586

O=CNNc1ccc(NC(=S)Nc2ccc(NNC=O)cc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.50
MAPT P10636 7/20 0.50
GAA P10253 5/20 0.50
KDM4E B2RXH2 1/20 0.50
THRB P10828 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
CYP3A4 P08684 2/20 0.46
TAS2R38 P59533 1/20 0.46
HSD17B10 Q99714 1/20 0.46
KMT2A Q03164 5/20 0.44
LMNA P02545 3/20 0.44
MAOA P21397 2/20 0.44
MAOB P27338 2/20 0.44
MEN1 O00255 4/20 0.43
POLB P06746 1/20 0.43
RAB9A P51151 1/20 0.42
MAPK1 P28482 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
CYP1A2 P05177 1/20 0.41
CYP2C19 P33261 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9174022 0.93 ALDH1A1 (0.61) ALDH1A1MAPTGAAKDM4EL3MBTL1
SCHEMBL6670322 0.89 ALDH1A1 (0.53) ALDH1A1MAPTGAAKDM4EL3MBTL1
SCHEMBL11687936 0.87 CYP1A2 (0.61) ALDH1A1MAPTGAAKDM4EKMT2A
SCHEMBL11683582 0.87 IDO1 (0.57) ALDH1A1MAPTGAAKDM4ETHRB
SCHEMBL8762360 0.84 MAPT (0.50) ALDH1A1MAPTGAAKDM4EKMT2A
SCHEMBL11309583 0.84 GAA (0.60) ALDH1A1MAPTGAAKDM4ECYP3A4
SCHEMBL11313130 0.84 GAA (0.58) ALDH1A1MAPTGAAKDM4ETHRB
SCHEMBL10416379 0.84 ALDH1A1 (0.50) ALDH1A1MAPTGAAL3MBTL1CYP3A4
SCHEMBL11344785 0.83 KDM4E (0.60) ALDH1A1MAPTGAAKDM4ECYP3A4
SCHEMBL9785826 0.83 ALDH1A1 (0.58) ALDH1A1GAAKDM4EL3MBTL1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4030925-A Photographic compositions and elements including internal latent image silver halide grains and acylhydrazinophenylthiourea nucleating agents therefor EASTMAN KODAK COMPANY (US) 1977-06-21 US claimed
US-4031127-A Acyl hydrazino thiourea derivatives as photographic nucleating agents EASTMAN KODAK COMPANY (US) 1977-06-21 US claimed
EP-0672945-B1 Silver halide color photographic light-sensitive material KONISHIROKU PHOTO IND (JP) 2001-06-13 EP disclosed
EP-0653673-B1 Silver halide color photographic light-sensitive material and image-forming process KONISHIROKU PHOTO IND (JP) 2000-04-26 EP disclosed
EP-0588649-B1 Positive type color light sensitive material and the image forming process therefor KONISHIROKU PHOTO IND (JP) 1999-12-08 EP disclosed
US-5981154-A USED FOR COLOR PROOF WHICH IS CAPABLE OF GIVING A COLOR PROOF HAVING IMPROVED CLOSENESS TO PRINT IMAGE QUALITY AND A STABLE TONE IMAGE KONICA CORPORATION (JP) 1999-11-09 US disclosed
EP-0588641-B1 Light-sensitive silver halide color photographic material and process for preparing color proof KONISHIROKU PHOTO IND (JP) 1999-02-10 EP disclosed
EP-0588639-B1 Silver halide color photographic photosensitive material and color proof preparation process KONISHIROKU PHOTO IND (JP) 1999-02-03 EP disclosed
EP-0585062-B1 Silver halide color photographic-light sensitive material and the image-forming process thereof KONISHIROKU PHOTO IND (JP) 1998-12-09 EP disclosed
EP-0723192-B1 Silver halide color photographic light-sensitive material and method of preparing color proof therefrom KONISHIROKU PHOTO IND (JP) 1998-05-27 EP disclosed
US-5541040-A PROVIDING MATERIAL HAVING SILVER HALIDE EMULSION LAYERS WITH DIFFERENT SPECTRAL SENSITIVITIES INCLUDING ONE LAYER SENSITIVE TO ALL WAVELENGTHS, EXPOSING TO LIGHT OF EACH WAVELENGTH, DEVELOPING KONICA CORPORATION (JP) 1996-07-30 US disclosed
US-4749644-A DIRECT POSITIVES; STABILITY, SMOOTHNESS, IMAGE QUALITY; COLOR FILM KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1988-06-07 US disclosed
EP-0264192-A2 Direct positive silver halide light-sensitive photographic material KONICA CORPORATION (JP) 1988-04-20 EP disclosed
EP-0204530-A2 Method for forming direct positive color image KONICA CORPORATION (JP) 1986-12-10 EP disclosed
EP-0190512-A2 Positive image forming method KONICA CORPORATION (JP) 1986-08-13 EP disclosed
US-4279987-A 2,5-DIHYDROXY-BIPHENYL COMPOUNDS ADDED AS DEVELOPMENT ACCELERATORS KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1981-07-21 US disclosed
US-4268621-A Direct positive photographic material KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1981-05-19 US disclosed
US-4243739-A HYDRAZIDE FUJI PHOTO FILM CO., LTD. (JP) 1981-01-06 US disclosed
US-4030925-A Photographic compositions and elements including internal latent image silver halide grains and acylhydrazinophenylthiourea nucleating agents therefor EASTMAN KODAK COMPANY (US) 1977-06-21 US disclosed
US-4031127-A Acyl hydrazino thiourea derivatives as photographic nucleating agents EASTMAN KODAK COMPANY (US) 1977-06-21 US disclosed