Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LSS | P48449 | 12/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7687793 | 0.83 | LSS (0.61) | LSSMAPTRAB9ALMNAMEN1 | |
| Hydrochloric Acid SCHEMBL7687465 | 0.82 | LSS (0.60) | LSSMAPTRAB9ALMNAMEN1 | |
| Fumaric Acid SCHEMBL7687488 | 0.80 | LSS (0.56) | LSSLMNAALDH1A1FFAR4 | |
| SCHEMBL7681502 | 0.76 | LSS (0.74) | LSSMEN1KMT2A | |
| SCHEMBL8035143 | 0.76 | LSS (0.60) | LSSMEN1KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL8035630 | 0.75 | LSS (0.60) | LSSMAPTRAB9ALMNAMEN1 | |
| SCHEMBL17358772 | 0.74 | LSS (1.00) | LSS | |
| SCHEMBL7687943 | 0.74 | LSS (1.00) | LSS | |
| Hydrochloric Acid SCHEMBL7681382 | 0.74 | LSS (0.98) | LSS | |
| SCHEMBL7688273 | 0.71 | LSS (0.67) | LSSMEN1KMT2AFFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0778264-B1 | Tertiary amines having antimycotic and cholesterol lowering activity | HOFFMANN LA ROCHE (CH) | 2001-07-11 | — | — | EP | claimed |