Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | LSS | P48449 | 7/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | TEAD1 | P28347 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7767805 | 1.00 | MAOB (0.37) | MAOBLSSHDAC1HDAC8GAA | |
| SCHEMBL7767803 | 1.00 | MAOB (0.37) | MAOBLSSHDAC1HDAC8GAA | |
| SCHEMBL8019187 | 0.88 | MAOB (0.42) | MAOBTAAR1TEAD1 | |
| SCHEMBL8019185 | 0.88 | MAOB (0.42) | MAOBTAAR1TEAD1 | |
| SCHEMBL7762543 | 0.88 | MAOB (0.34) | MAOB | |
| SCHEMBL7762539 | 0.88 | MAOB (0.34) | MAOB | |
| SCHEMBL7762546 | 0.88 | MAOB (0.34) | MAOB | |
| SCHEMBL7769784 | 0.88 | HRH3 (0.33) | MAOBTAAR1 | |
| SCHEMBL7769781 | 0.88 | HRH3 (0.33) | MAOBTAAR1 | |
| SCHEMBL7769787 | 0.88 | HRH3 (0.33) | MAOBTAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0727428-B1 | Novel silacyclohexane compounds, preparation thereof, liquid crystal compositions comprising the same, and liquid crystal devices comprising the compositions | SHINETSU CHEMICAL CO (JP) | 2001-06-06 | — | — | EP | disclosed |
| US-5665271-A | Silacyclohexane compounds, preparation thereof, liquid crystal compositions comprising the same, and liquid crystal devices comprising the compositions | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1997-09-09 | — | — | US | disclosed |
| EP-0727428-A1 | Novel silacyclohexane compounds, preparation thereof, liquid crystal compositions comprising the same, and liquid crystal devices comprising the compositions | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1996-08-21 | — | — | EP | disclosed |