Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.60 |
| ▸ | DNM1 | Q05193 | 10/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.48 |
| ▸ | RAD52 | P43351 | 2/20 | 0.48 |
| ▸ | RECQL | P46063 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.45 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.45 |
| ▸ | LSS | P48449 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL61318 | 1.00 | HTT (0.60) | HTTDNM1LMNAKMT2AHSP90AA1 | |
| SCHEMBL28005833 | 1.00 | HTT (0.60) | HTTDNM1LMNAKMT2AHSP90AA1 | |
| SCHEMBL27542884 | 1.00 | HTT (0.60) | HTTDNM1LMNAKMT2AHSP90AA1 | |
| SCHEMBL5880997 | 1.00 | HTT (0.60) | HTTDNM1LMNAKMT2AHSP90AA1 | |
| SCHEMBL10806075 | 1.00 | HTT (0.60) | HTTDNM1LMNAKMT2AHSP90AA1 | |
| Didecyldimethylammonium SCHEMBL3936454 | 1.00 | HTT (0.60) | HTTDNM1LMNAKMT2AHSP90AA1 | |
| SCHEMBL5803866 | 1.00 | HTT (0.60) | HTTDNM1LMNAKMT2AHSP90AA1 | |
| SCHEMBL10420709 | 1.00 | HTT (0.60) | HTTDNM1LMNAKMT2AHSP90AA1 | |
| SCHEMBL1547985 | 1.00 | HTT (0.60) | HTTDNM1LMNAKMT2AHSP90AA1 | |
| SCHEMBL3943087 | 0.98 | HTT (0.58) | HTTDNM1LMNAKMT2AHSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1104285-A1 | OPAQUE CONDITIONING COMPOSITION | UNILEVER PLC (GB) | 2001-06-06 | — | — | EP | disclosed |
| US-6149899-A | A HAIR CONDITIONER MIXTURE COMPRISING QUATERNIZED AMMONIUM COMPOUNDS, ONE WITH A MONOALKYL GROUP HAVING 16 TO 22 CARBON ATOMS AND ONE WITH DIALKYL GROUPS HAVING 20 TO 22 CARBON ATOMS, AND A FATTY ALCOHOL | HELENE CURTIS, INC. (US) | 2000-11-21 | — | — | US | disclosed |
| WO-2000007563-A1 | OPAQUE CONDITIONING COMPOSITION | UNILEVER PLC (GB) | 2000-02-17 | — | — | WO | disclosed |