Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.60 |
| ▸ | DNM1 | Q05193 | 10/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.48 |
| ▸ | RAD52 | P43351 | 2/20 | 0.48 |
| ▸ | RECQL | P46063 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.45 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.45 |
| ▸ | LSS | P48449 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL61318 | 1.00 | HTT (0.60) | HTTDNM1LMNAKMT2AHSP90AA1 | |
| SCHEMBL28005833 | 1.00 | HTT (0.60) | HTTDNM1LMNAKMT2AHSP90AA1 | |
| SCHEMBL27542884 | 1.00 | HTT (0.60) | HTTDNM1LMNAKMT2AHSP90AA1 | |
| SCHEMBL10806075 | 1.00 | HTT (0.60) | HTTDNM1LMNAKMT2AHSP90AA1 | |
| SCHEMBL7767862 | 1.00 | HTT (0.60) | HTTDNM1LMNAKMT2AHSP90AA1 | |
| Didecyldimethylammonium SCHEMBL3936454 | 1.00 | HTT (0.60) | HTTDNM1LMNAKMT2AHSP90AA1 | |
| SCHEMBL5803866 | 1.00 | HTT (0.60) | HTTDNM1LMNAKMT2AHSP90AA1 | |
| SCHEMBL10420709 | 1.00 | HTT (0.60) | HTTDNM1LMNAKMT2AHSP90AA1 | |
| SCHEMBL1547985 | 1.00 | HTT (0.60) | HTTDNM1LMNAKMT2AHSP90AA1 | |
| SCHEMBL3943087 | 0.98 | HTT (0.58) | HTTDNM1LMNAKMT2AHSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 87 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4460644-A | Polyurethane foam impregnated with or coated with fabric conditioning agent, anti-microbial agent and anti-discolorant | BEECHAM INC. (US) | 1984-07-17 | — | — | US | claimed |
| US-4110498-A | FABRIC TREATMENT COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 1978-08-29 | — | — | US | claimed |
| US-4022938-A | IMPARTING SOFTENING AND ANTISTATIC PROPERTIES DURING MACHINE DRYING WITH A CATIONIC SOFTENER AND A SORBITAN ESTER | THE PROCTER & GAMBLE COMPANY (US) | 1977-05-10 | — | — | US | claimed |
| US-12606779-B2 | Active agent-containing articles | THE PROCTER & GAMBLE COMPANY (US) | 2026-04-21 | — | — | US | disclosed |
| CN-119855583-A | Composition for cosmetic treatment of keratin fibres | 碧昂赛恩斯公司 | 2025-04-18 | — | — | CN | disclosed |
| EP-4380537-A1 | WATER INSOLUBLE FIBROUS ARTICLES COMPRISING ACTIVE AGENTS | The Procter & Gamble Company (US) | 2024-06-12 | — | — | EP | disclosed |
| CN-117642144-A | Water insoluble fibrous article comprising active agent | 宝洁公司 | 2024-03-01 | — | — | CN | disclosed |
| CN-112512488-B | External gel preparation for skin | 株式会社资生堂 | 2024-02-02 | — | — | CN | disclosed |
| US-11845911-B2 | Active agent-containing fibrous structure articles | THE PROCTER & GAMBLE COMPANY (US) | 2023-12-19 | — | — | US | disclosed |
| US-20230399595-A1 | Active Agent-Containing Articles | PROCTER & GAMBLE (US) | 2023-12-14 | — | — | US | disclosed |
| US-11781095-B2 | Active agent-containing articles | THE PROCTER & GAMBLE COMPANY (US) | 2023-10-10 | — | — | US | disclosed |
| EP-0255711-A2 | Article for conditioning fabrics in a laundry dryer | DOW CORNING CORPORATION (US) | 1988-02-10 | — | — | EP | disclosed |
| US-4711730-A | RINSE- AND DRIER-ADDED FABRIC CONDITIONERS; LAUNDRY DETERGENTS | THE PROCTER & GAMBLE COMPANY (US) | 1987-12-08 | — | — | US | disclosed |
| EP-0241985-A2 | Capped 1,2-propylene terephthalate-polyoxyethylene terephthalate polyesters useful as soil release agents | THE PROCTER & GAMBLE COMPANY (US) | 1987-10-21 | — | — | EP | disclosed |
| US-4460644-A | Polyurethane foam impregnated with or coated with fabric conditioning agent, anti-microbial agent and anti-discolorant | BEECHAM INC. (US) | 1984-07-17 | — | — | US | disclosed |
| US-4214038-A | Fabric treatment compositions containing polyglycerol esters | THE PROCTER & GAMBLE COMPANY (US) | 1980-07-22 | — | — | US | disclosed |
| US-4110498-A | FABRIC TREATMENT COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 1978-08-29 | — | — | US | disclosed |
| US-4103047-A | CATIONIC ANTISTATIC-FABRIC SOFTENER CONTAINING A FATTY ALKYL SORBITAN ESTER FOR USE IN A DRYER | THE PROCTER & GAMBLE COMPANY (US) | 1978-07-25 | — | — | US | disclosed |
| US-4085052-A | Fabric treatment compositions | THE PROCTER & GAMBLE COMPANY (US) | 1978-04-18 | — | — | US | disclosed |
| US-4022938-A | IMPARTING SOFTENING AND ANTISTATIC PROPERTIES DURING MACHINE DRYING WITH A CATIONIC SOFTENER AND A SORBITAN ESTER | THE PROCTER & GAMBLE COMPANY (US) | 1977-05-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11781095-B2 | Active agent-containing articles | POLR1C, MPO, MMP8 | HTT 505/4885DNM1 1611/4885LMNA 2737/4885 |
| US-20230399595-A1 | Active Agent-Containing Articles | POLR1C, MPO, MMP8 | HTT 505/4885DNM1 1611/4885LMNA 2737/4885 |
| US-12606779-B2 | Active agent-containing articles | ASH2L, CD69, WASHC5 | HTT 1908/4885DNM1 4646/4885LMNA 2688/4885 |
| US-11845911-B2 | Active agent-containing fibrous structure articles | MMP1, FIBP, MMP8 | HTT 600/4885DNM1 2462/4885LMNA 995/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.