Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 1.00 |
| ▸ | MEN1 | O00255 | 5/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 5/20 | 1.00 |
| ▸ | MAPT | P10636 | 4/20 | 1.00 |
| ▸ | THRB | P10828 | 2/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 1.00 |
| ▸ | GFER | P55789 | 1/20 | 1.00 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 1.00 |
| ▸ | BCHE | P06276 | 1/20 | 0.71 |
| ▸ | ACHE | P22303 | 1/20 | 0.71 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.62 |
| ▸ | GAA | P10253 | 3/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | FAAH | O00519 | 6/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5344100 | 0.86 | ALDH1A1 (0.76) | ALDH1A1MEN1KMT2AMAPTTHRB | |
| SCHEMBL8063648 | 0.86 | ALDH1A1 (0.82) | ALDH1A1MEN1KMT2AMAPTTHRB | |
| SCHEMBL2475633 | 0.83 | BCHE (0.84) | ALDH1A1MEN1KMT2AMAPTTHRB | |
| Phenyl Phenylcarbamate SCHEMBL272994 | 0.82 | ALDH1A1 (0.76) | ALDH1A1MEN1KMT2AMAPTTHRB | |
| Hydrochloric Acid SCHEMBL29406709 | 0.82 | BCHE (0.97) | ALDH1A1MEN1KMT2AMAPTTHRB | |
| SCHEMBL11717564 | 0.82 | ALDH1A1 (0.68) | ALDH1A1MEN1KMT2AMAPTTHRB | |
| SCHEMBL6037499 | 0.81 | ALDH1A1 (0.75) | ALDH1A1MEN1KMT2AMAPTTHRB | |
| Hydrochloric Acid SCHEMBL11719668 | 0.81 | ALDH1A1 (0.67) | ALDH1A1MEN1KMT2AMAPTTHRB | |
| SCHEMBL27994620 | 0.80 | ALDH1A1 (0.67) | ALDH1A1MEN1KMT2AMAPTTHRB | |
| Phenyl 4-Methoxyphenylcarbamate SCHEMBL11183948 | 0.80 | ALDH1A1 (0.90) | ALDH1A1MEN1KMT2AMAPTTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0718281-B1 | CYCLOHEXANEDIUREA DERIVATIVE AND PROCESS FOR PRODUCING THE SAME | NISSIN FOOD PRODUCTS LTD (JP) | 2001-06-27 | — | — | EP | disclosed |
| US-5733931-A | ANTICHOLESTEROL AGENTS | NISSIN FOOD PRODUCTS CO., LTD. (JP) | 1998-03-31 | — | — | US | disclosed |
| EP-0718281-A1 | CYCLOHEXANEDIUREA DERIVATIVE AND PROCESS FOR PRODUCING THE SAME | NISSIN FOOD PRODUCTS CO., LTD. (JP) | 1996-06-26 | — | — | EP | disclosed |
| EP-0144853-B1 | SEMICARBAZIDE DERIVATIVES, PROCESSES FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-09-26 | — | — | EP | disclosed |
| US-4725608-A | ANTIINFLAMMATORY, ANALGESICS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-02-16 | — | — | US | disclosed |
| EP-0144853-A2 | Semicarbazide derivatives, processes for preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1985-06-19 | — | — | EP | disclosed |