Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.34 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.33 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | THRB | P10828 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | APAF1 | O14727 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | THRA | P10827 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAD52 | P43351 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7767968 | 1.00 | S1PR1 (0.34) | S1PR1SMN1; SMN2GLAS1PR2S1PR3 | |
| SCHEMBL7767971 | 1.00 | S1PR1 (0.34) | S1PR1SMN1; SMN2GLAS1PR2S1PR3 | |
| SCHEMBL7769733 | 0.93 | S1PR1 (0.34) | S1PR1SMN1; SMN2GLAS1PR2S1PR3 | |
| SCHEMBL7769731 | 0.93 | S1PR1 (0.34) | S1PR1SMN1; SMN2GLAS1PR2S1PR3 | |
| SCHEMBL7769725 | 0.93 | S1PR1 (0.34) | S1PR1SMN1; SMN2GLAS1PR2S1PR3 | |
| SCHEMBL7765299 | 0.92 | KDM1A (0.34) | S1PR1S1PR2S1PR3LPAR2ITGB3 | |
| SCHEMBL7765309 | 0.92 | KDM1A (0.34) | S1PR1S1PR2S1PR3LPAR2ITGB3 | |
| SCHEMBL7765303 | 0.92 | KDM1A (0.34) | S1PR1S1PR2S1PR3LPAR2ITGB3 | |
| SCHEMBL7765302 | 0.89 | HTR2A (0.32) | S1PR1S1PR2S1PR3LPAR2ITGB3 | |
| SCHEMBL7765298 | 0.89 | HTR2A (0.32) | S1PR1S1PR2S1PR3LPAR2ITGB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0727428-B1 | Novel silacyclohexane compounds, preparation thereof, liquid crystal compositions comprising the same, and liquid crystal devices comprising the compositions | SHINETSU CHEMICAL CO (JP) | 2001-06-06 | — | — | EP | disclosed |
| US-5665271-A | Silacyclohexane compounds, preparation thereof, liquid crystal compositions comprising the same, and liquid crystal devices comprising the compositions | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1997-09-09 | — | — | US | disclosed |
| EP-0727428-A1 | Novel silacyclohexane compounds, preparation thereof, liquid crystal compositions comprising the same, and liquid crystal devices comprising the compositions | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1996-08-21 | — | — | EP | disclosed |