Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.44 |
| ▸ | RAB9A | P51151 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | MMP14 | P50281 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.42 |
| ▸ | MITF | O75030 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 3/20 | 0.36 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | F2 | P00734 | 3/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.35 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7768059 | 1.00 | NPC1 (0.44) | NPC1RAB9AMAPTKMT2AMEN1 | |
| SCHEMBL7767891 | 0.89 | MAPT (0.57) | NPC1RAB9AMAPTKMT2AMEN1 | |
| SCHEMBL7767895 | 0.89 | MAPT (0.57) | NPC1RAB9AMAPTKMT2AMEN1 | |
| SCHEMBL7769138 | 0.86 | MAPT (0.40) | NPC1RAB9AMAPTKMT2AMEN1 | |
| SCHEMBL7769136 | 0.86 | MAPT (0.40) | NPC1RAB9AMAPTKMT2AMEN1 | |
| SCHEMBL7769131 | 0.86 | NPC1 (0.41) | NPC1RAB9AMAPTKMT2AMEN1 | |
| SCHEMBL7769130 | 0.86 | NPC1 (0.41) | NPC1RAB9AMAPTKMT2AMEN1 | |
| SCHEMBL7764276 | 0.85 | MAPT (0.37) | NPC1RAB9AMAPTKMT2AMEN1 | |
| SCHEMBL7764270 | 0.85 | MAPT (0.37) | NPC1RAB9AMAPTKMT2AMEN1 | |
| SCHEMBL7768308 | 0.85 | PTGS1 (0.43) | NPC1RAB9AMAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0740690-B1 | MONOAZO DYES CONTAINING A FLUOROSULPHONYL GROUP AND USE THEREOF | SYNGENTA LTD (GB) | 2001-06-20 | — | — | EP | claimed |
| EP-0740690-B1 | MONOAZO DYES CONTAINING A FLUOROSULPHONYL GROUP AND USE THEREOF | SYNGENTA LTD (GB) | 2001-06-20 | — | — | EP | disclosed |
| US-5739299-A | GOOD WET FASTNESS AND LIGHT FASTNESS PROPERTIES | ZENECA LIMITED (GB) | 1998-04-14 | — | — | US | disclosed |