SCHEMBL7769138

SCHEMBL7769138

CCN(CC)c1ccc(N=Nc2cc(S(=O)(=O)F)ccc2C)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 10/20 0.40
ALDH1A1 P00352 8/20 0.40
RAB9A P51151 6/20 0.40
NPC1 O15118 5/20 0.40
LMNA P02545 4/20 0.40
SMN1; SMN2 Q16637 3/20 0.40
TDP1 Q9NUW8 3/20 0.40
L3MBTL1 Q9Y468 3/20 0.40
MAPK1 P28482 2/20 0.40
ALPL P05186 1/20 0.40
ALPI P09923 1/20 0.40
ALPG P10696 1/20 0.40
NFKB1 P19838 1/20 0.40
NFKB2 Q00653 1/20 0.40
RELA Q04206 1/20 0.40
KMT2A Q03164 6/20 0.40
MEN1 O00255 5/20 0.40
KDM4E B2RXH2 2/20 0.40
CNR2 P34972 5/20 0.39
CRHBP P24387 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7769136 1.00 MAPT (0.40) MAPTALDH1A1RAB9ANPC1LMNA
SCHEMBL7768059 0.86 NPC1 (0.44) MAPTALDH1A1RAB9ANPC1LMNA
SCHEMBL7768058 0.86 NPC1 (0.44) MAPTALDH1A1RAB9ANPC1LMNA
SCHEMBL7768216 0.86 MAPT (0.48) MAPTALDH1A1RAB9ANPC1LMNA
SCHEMBL7768219 0.86 MAPT (0.48) MAPTALDH1A1RAB9ANPC1LMNA
SCHEMBL7764264 0.83 MAPT (0.33) MAPTALDH1A1RAB9ANPC1LMNA
SCHEMBL8727698 0.79 ALDH1A1 (0.33) MAPTALDH1A1RAB9ANPC1LMNA
SCHEMBL7768072 0.76 BRD4 (0.41) MAPTALDH1A1LMNAKMT2ACA12
SCHEMBL7768073 0.76 BRD4 (0.41) MAPTALDH1A1LMNAKMT2ACA12
SCHEMBL7772206 0.76 KMT2A (0.40) MAPTALDH1A1RAB9ANPC1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0740690-B1 MONOAZO DYES CONTAINING A FLUOROSULPHONYL GROUP AND USE THEREOF SYNGENTA LTD (GB) 2001-06-20 EP claimed
EP-0740690-B1 MONOAZO DYES CONTAINING A FLUOROSULPHONYL GROUP AND USE THEREOF SYNGENTA LTD (GB) 2001-06-20 EP disclosed
US-5739299-A GOOD WET FASTNESS AND LIGHT FASTNESS PROPERTIES ZENECA LIMITED (GB) 1998-04-14 US disclosed