Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC9 | O60706 | 2/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3942504 | 1.00 | ABCC9 (0.39) | ABCC9EPHX1TSHRLMNAALDH1A1 | |
| SCHEMBL13460693 | 1.00 | ABCC9 (0.39) | ABCC9EPHX1TSHRLMNAALDH1A1 | |
| SCHEMBL14765559 | 1.00 | ABCC9 (0.39) | ABCC9EPHX1TSHRLMNAALDH1A1 | |
| SCHEMBL3942509 | 1.00 | ABCC9 (0.39) | ABCC9EPHX1TSHRLMNAALDH1A1 | |
| SCHEMBL3947212 | 1.00 | ABCC9 (0.39) | ABCC9EPHX1TSHRLMNAALDH1A1 | |
| SCHEMBL12961911 | 0.88 | TSHR (0.42) | EPHX1TSHRLMNAALDH1A1TDP1 | |
| SCHEMBL3948133 | 0.88 | TSHR (0.42) | EPHX1TSHRLMNAALDH1A1TDP1 | |
| SCHEMBL3946596 | 0.88 | TSHR (0.42) | EPHX1TSHRLMNAALDH1A1TDP1 | |
| SCHEMBL3946593 | 0.88 | TSHR (0.42) | EPHX1TSHRLMNAALDH1A1TDP1 | |
| SCHEMBL9767087 | 0.83 | AKR1B1 (0.39) | LMNAALDH1A1HTTMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1109801-A1 | SUBSTITUTED DIHYDROBENZOPYRANS USEFUL AS ANTIARRHYTHMIC AGENTS | THE PROCTER & GAMBLE COMPANY (US) | 2001-06-27 | — | — | EP | disclosed |
| WO-2000014084-A1 | SUBSTITUTED DIHYDROBENZOPYRANS USEFUL AS ANTIARRHYTHMIC AGENTS | THE PROCTER & GAMBLE COMPANY (US) | 2000-03-16 | — | — | WO | disclosed |