Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.75 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.75 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 5/20 | 0.60 |
| ▸ | LMNA | P02545 | 4/20 | 0.60 |
| ▸ | HPGD | P15428 | 3/20 | 0.60 |
| ▸ | ESR1 | P03372 | 1/20 | 0.60 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.60 |
| ▸ | PKM | P14618 | 1/20 | 0.60 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | LIG1 | P18858 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1758224 | 0.90 | HTT (0.60) | HTTSMN1; SMN2TDP1POLBL3MBTL1 | |
| SCHEMBL30355061 | 0.90 | HTT (0.60) | HTTSMN1; SMN2TDP1POLBL3MBTL1 | |
| SCHEMBL9544691 | 0.86 | HTT (0.56) | HTTSMN1; SMN2TDP1POLBL3MBTL1 | |
| SCHEMBL1758781 | 0.84 | HTT (0.75) | HTTSMN1; SMN2TDP1POLBL3MBTL1 | |
| SCHEMBL12337417 | 0.84 | ALDH1A1 (0.61) | HTTSMN1; SMN2TDP1POLBL3MBTL1 | |
| SCHEMBL10420722 | 0.84 | CA1 (0.61) | HTTSMN1; SMN2TDP1POLBL3MBTL1 | |
| SCHEMBL10421109 | 0.84 | HTT (0.64) | HTTSMN1; SMN2TDP1POLBL3MBTL1 | |
| SCHEMBL10775755 | 0.83 | MAPK1 (0.60) | HTTSMN1; SMN2TDP1POLBL3MBTL1 | |
| SCHEMBL9012657 | 0.82 | HTT (0.71) | HTTSMN1; SMN2TDP1POLBL3MBTL1 | |
| SCHEMBL31574447 | 0.81 | HTT (0.70) | HTTSMN1; SMN2TDP1POLBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0847432-B1 | POLYMERIZABLE LIQUID-CRYSTALLINE COMPOUNDS | BASF AG (DE) | 2001-06-27 | — | — | EP | disclosed |
| EP-0847432-A2 | POLYMERIZABLE LIQUID-CRYSTALLINE COMPOUNDS | BASF AKTIENGESELLSCHAFT (DE) | 1998-06-17 | — | — | EP | disclosed |
| WO-1997000600-A2 | POLYMERIZABLE LIQUID-CRYSTALLINE COMPOUNDS | BASF AKTIENGESELLSCHAFT (DE) | 1997-01-09 | — | — | WO | disclosed |