Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7768540 | 1.00 | MEN1 (0.42) | MEN1USP2ALDH1A1MAPTKMT2A | |
| SCHEMBL7767025 | 0.90 | MEN1 (0.34) | MEN1USP2ALDH1A1MAPTKMT2A | |
| SCHEMBL4418217 | 0.86 | PDE4A (0.35) | MEN1USP2ALDH1A1MAPTKMT2A | |
| SCHEMBL3168963 | 0.86 | PDE4A (0.35) | MEN1USP2ALDH1A1MAPTKMT2A | |
| SCHEMBL16176158 | 0.80 | MEN1 (0.38) | MEN1USP2ALDH1A1MAPTKMT2A | |
| SCHEMBL9444633 | 0.80 | PDE4A (0.48) | USP2KDM4EL3MBTL1 | |
| SCHEMBL221668 | 0.77 | HRH3 (0.34) | ALDH1A1KMT2AHRH3PTGS1KCNH2 | |
| SCHEMBL14524268 | 0.77 | KDM4E (0.33) | ALDH1A1HRH3KDM4EGLAL3MBTL1 | |
| SCHEMBL13426840 | 0.77 | MEN1 (0.41) | MEN1USP2ALDH1A1MAPTKMT2A | |
| SCHEMBL9769659 | 0.73 | HRH3 (0.33) | USP2HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0741128-B1 | Sulphuric acid esters of sugar alcohols for the inhibition of the migration and proliferation of smooth muscle cells of the vascular walls | HOFFMANN LA ROCHE (CH) | 2001-06-20 | — | — | EP | disclosed |
| US-5830920-A | PREVENTION GROWTH OF SMOOTH MUSCLE CELLS | HOFFMANN-LA ROCHE INC. (US) | 1998-11-03 | — | — | US | disclosed |
| EP-0741128-A2 | Sulphuric acid esters of sugar alcohols for the inhibition of the migration and proliferation of smooth muscle cells of the vascular walls | F. HOFFMANN-LA ROCHE AG (CH) | 1996-11-06 | — | — | EP | disclosed |