SCHEMBL4418217

SCHEMBL4418217

O=C(NC(CO)(CO)CO)C(O)C(O)CO

nearest known ligand 0.35

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
PDE4A P27815 1/20 0.35
LMNA P02545 2/20 0.33
MEN1 O00255 1/20 0.32
USP2 O75604 1/20 0.32
ALDH1A1 P00352 1/20 0.32
MAPT P10636 1/20 0.32
KMT2A Q03164 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3168963 1.00 PDE4A (0.35) PDE4ALMNAMEN1USP2ALDH1A1
SCHEMBL7768536 0.86 MEN1 (0.42) MEN1USP2ALDH1A1MAPTKMT2A
SCHEMBL9444677 0.86 PDE4A (0.50) PDE4ALMNAUSP2L3MBTL1
SCHEMBL9444633 0.84 PDE4A (0.48) PDE4ALMNAUSP2L3MBTL1
SCHEMBL7767025 0.82 MEN1 (0.34) PDE4ALMNAMEN1USP2ALDH1A1
SCHEMBL14060467 0.72 PGD (0.50) PDE4ALMNAMEN1USP2ALDH1A1
SCHEMBL9876668 0.70 KDM4E (0.39) PDE4ALMNAMEN1USP2ALDH1A1
SCHEMBL221668 0.70 HRH3 (0.34) ALDH1A1KMT2A
SCHEMBL27915989 0.67 MEN1 (0.39) PDE4ALMNAMEN1USP2ALDH1A1
SCHEMBL3172480 0.67 MEN1 (0.39) PDE4ALMNAMEN1USP2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2021345-A1 HYDROXYLATED AMIDE SKIN MOISTURIZER L'Oreal (FR) 2009-02-11 EP claimed
WO-2007137925-A1 HYDROXYLATED AMIDE SKIN MOISTURIZER L'OREAL (FR) 2007-12-06 WO claimed