SCHEMBL7768564

SCHEMBL7768564

CCN(CC)CC.N=C=O

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 1/20 0.33
CHRM4 P08173 1/20 0.33
CHRM5 P08912 1/20 0.33
CHRM1 P11229 1/20 0.33
CHRM3 P20309 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL29020366 0.97 CHRM2 (0.32) CHRM2CHRM4CHRM5CHRM1CHRM3
Carbon Dioxide SCHEMBL7040864 0.85 CHRM2 (0.36) CHRM2CHRM4CHRM5CHRM1CHRM3
Carbimide SCHEMBL4053621 0.85 CHRM2 (0.31) CHRM2CHRM4CHRM5CHRM1CHRM3
Carbimide SCHEMBL28645014 0.81
SCHEMBL28265390 0.79 CHRM2 (0.33) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL28187686 0.79 CHRM2 (0.39) CHRM2CHRM4CHRM5CHRM1CHRM3
Propane SCHEMBL25170512 0.76
Propane SCHEMBL1304230 0.76
Propane SCHEMBL11799721 0.76
Propane SCHEMBL111122 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1112303-A2 CURING OF RESINS Chemcolloids Limited (GB) 2001-07-04 EP claimed
WO-2000015694-A2 CURING OF RESINS CHEMCOLLOIDS LIMITED (GB) 2000-03-23 WO claimed
US-10391070-B2 Compositions and methods for treating neurological diseases or injury MUSC FOUNDATION FOR RESEARCH DEVELOPMENT (US) 2019-08-27 US disclosed
US-20180185306-A1 COMPOSITIONS AND METHODS FOR TREATING NEUROLOGICAL DISEASES OR INJURY MUSC FOUNDATION FOR RESEARCH DEVELOPMENT (US) 2018-07-05 US disclosed
US-9861596-B2 Compositions and methods for treating neurological diseases or injury MUSC FOUNDATION FOR RESEARCH DEVELOPMENT (US) 2018-01-09 US disclosed
CN-106146484-A Quinazoline derivant is as RAF kinase modulator and their method and purposes 埃姆比特生物科学公司 2016-11-23 CN disclosed
US-20150320702-A1 COMPOSITIONS AND METHODS FOR TREATING NEUROLOGICAL DISEASES OR INJURY MEDICAL UNIVERSITY OF SOUTH CAROLINA 2015-11-12 US disclosed
WO-2014074976-A1 COMPOSITIONS AND METHODS FOR TREATING NEUROLOGICAL DISEASES OR INJURY MUSC FOUNDATION FOR RESEARCH DEVELOPMENT (US) 2014-05-15 WO disclosed
EP-1112303-A2 CURING OF RESINS Chemcolloids Limited (GB) 2001-07-04 EP disclosed
WO-2000015694-A2 CURING OF RESINS CHEMCOLLOIDS LIMITED (GB) 2000-03-23 WO disclosed
US-5481035-A REACTING AMMONIUM ISOCYANATE WITH AMINES TO PRODUCE UREAS CHEMIE LINZ GESELLSCHAFT M.B.H. (AT) 1996-01-02 US disclosed
EP-0416236-B1 Process for the isolation isocyanic acid from a gaseous mixture of isocyanic acid and ammonia CHEMIE LINZ GMBH (AT) 1995-11-08 EP disclosed
EP-0410169-B1 Process for the preparation of asymmetrically substituted ureas, carbamates, thiocarbamates and substituted isocyanates CHEMIE LINZ GMBH (AT) 1994-12-14 EP disclosed
US-5248755-A With adduct of isocyanic acid and tertiary amine CHEMIE LINZ GESELLSCHAFT M.B.H. (AT) 1993-09-28 US disclosed
US-5223635-A Preparation of organic compounds using as a reactant an adduct of isocyanic acid and a tertiary amine or an ether CHEMIE LINZ GESELLSCHAFT M.B.H. (AT) 1993-06-29 US disclosed
US-5091553-A PROCESS FOR THE PREPARATION OF SUBSTITUTED ISOCYANATES CHEMIE LINZ GESELLSCHAFT M.B.H. (AT) 1992-02-25 US disclosed
EP-0468308-A2 Process for the preparation of beta-fluorinated alcohols BAYER AG (DE) 1992-01-29 EP disclosed
US-5078980-A Forming an adduct with an ether or tertiary amine, chemical intermediates for ureas, thiocarbamates and isocyanates CHEMIE LINZ GESELLSCHAFT M.B.H. (AT) 1992-01-07 US disclosed
EP-0416236-A2 Process for the isolation isocyanic acid from a gaseous mixture of isocyanic acid and ammonia Chemie Linz GmbH (AT) 1991-03-13 EP disclosed
EP-0410169-A2 Process for the preparation of asymmetrically substituted ureas, carbamates, thiocarbamates and substituted isocyanates Chemie Linz GmbH (AT) 1991-01-30 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10391070-B2 Compositions and methods for treating neurological diseases or injury PROC, GLS, NLN CHRM2 2099/4885CHRM4 3210/4885CHRM5 2753/4885
US-20150320702-A1 COMPOSITIONS AND METHODS FOR TREATING NEUROLOGICAL DISEASES OR INJURY PROC, GLS, NLN CHRM2 2099/4885CHRM4 3210/4885CHRM5 2753/4885
US-20180185306-A1 COMPOSITIONS AND METHODS FOR TREATING NEUROLOGICAL DISEASES OR INJURY PROC, GLS, NLN CHRM2 2099/4885CHRM4 3210/4885CHRM5 2753/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.