Butyrolactone

Butyrolactone

SCHEMBL7768880

O=C1CCCO1.OCCO

nearest known ligand 0.64

Full drug profile on Sugi Atlas →

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.64
CA9 Q16790 1/20 0.64
LMNA P02545 2/20 0.48
ALDH1A1 P00352 1/20 0.48
TP53 P04637 1/20 0.48
TSHR P16473 1/20 0.48
CYP2D6 P10635 1/20 0.33
CYP2C9 P11712 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Butyrolactone SCHEMBL8378156 0.95 CA1 (0.58) CA1CA9LMNAALDH1A1TP53
Ethylene Glycol SCHEMBL384287 0.93 CA1 (0.68) CA1CA9LMNAALDH1A1TP53
Ethylene Glycol SCHEMBL173829 0.93 CA1 (0.76) CA1CA9LMNAALDH1A1TP53
Ethylene Glycol SCHEMBL1239792 0.91 CA1 (0.73) CA1CA9LMNAALDH1A1TP53
Ethylene Glycol SCHEMBL8524424 0.91 CA1 (0.73) CA1CA9LMNAALDH1A1TP53
Ethylene Glycol SCHEMBL2287553 0.91 CA1 (0.65) CA1CA9LMNAALDH1A1TP53
Ethylene Glycol SCHEMBL1241937 0.91 CA1 (0.73) CA1CA9LMNAALDH1A1TP53
Ethylene Glycol SCHEMBL2281708 0.91 CA1 (0.73) CA1CA9LMNAALDH1A1TP53
Ethylene Glycol SCHEMBL11061791 0.91 CA1 (0.73) CA1CA9LMNAALDH1A1TP53
Ethylene Glycol SCHEMBL31356 0.91 CA1 (0.73) CA1CA9LMNAALDH1A1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4245278-A IN A POLAR ORGANIC SOLVENT AND WATER SPRAGUE ELECTRIC COMPANY (US) 1981-01-13 US claimed
CN-111246740-A Novel herbicidal compounds 马罗内生物创新公司 2020-06-05 CN disclosed
US-20140017216-A1 PESTICIDAL MIXTURES BAYER CROPSCIENCE LP (US) 2014-01-16 US disclosed
CN-101280094-A Bioactive aquagel-conductive polymer nanometer composite material and synthetic material thereof UNIV XIAMEN (CN) 2008-10-08 CN disclosed
EP-0749039-B1 A method of forming an imaging element comprising an auxiliary layer containing solvent- dispersible polymer particles EASTMAN KODAK CO (US) 2001-08-08 EP disclosed
EP-0749041-B1 Imaging element comprising an electrically-conductive layer and a protective overcoat layer containing solvent-dispersible polymer particles EASTMAN KODAK CO (US) 1999-08-11 EP disclosed
EP-0603410-B1 MOISTURE-PERMEABLE WATERPROOF CLOTH AND PRODUCTION THEREOF KOMATSU SEIREN CO (JP) 1998-09-02 EP disclosed
US-5692936-A PROTECTIVE COATINGS COMPRISING A POLYETHERURETHANE OR A POLYESTERURETHANE COPOLYMERS OR A TERPOLYMER OF POLYESTER, POLYETHER AND POLYURETHANE; VAPOR PERMEABILITY AT HIGH TEMPERTURE, IMPERVIOUS AT LOW TEMPERATURE KOMATSU SEIVEN CO., LTD. (JP) 1997-12-02 US disclosed
EP-0749039-A1 Imaging element comprising an auxiliary layer containing solvent-dispersible polymer particles EASTMAN KODAK COMPANY (US) 1996-12-18 EP disclosed
EP-0749041-A1 Imaging element comprising an electrically-conductive layer and a protective overcoat layer containing solvent-dispersible polymer particles EASTMAN KODAK COMPANY (US) 1996-12-18 EP disclosed
EP-0603410-A1 MOISTURE-PERMEABLE WATERPROOF CLOTH AND PRODUCTION THEREOF KOMATSU SEIREN CO., LTD. (JP) 1994-06-29 EP disclosed
EP-0343984-A2 Color filter array for liquid crystal display device HOECHST CELANESE CORPORATION (US) 1989-11-29 EP disclosed