Butyrolactone

Butyrolactone

SCHEMBL8378156

C=C.O=C1CCCO1.OCCO

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.58
CA9 Q16790 1/20 0.58
ALDH1A1 P00352 1/20 0.43
LMNA P02545 1/20 0.43
TP53 P04637 1/20 0.43
TSHR P16473 1/20 0.43
CYP2D6 P10635 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Butyrolactone SCHEMBL7768880 0.95 CA1 (0.64) CA1CA9ALDH1A1LMNATP53
Ethylene Glycol SCHEMBL3174512 0.91 CA1 (0.67) CA1CA9ALDH1A1LMNATP53
Ethylene Glycol SCHEMBL384287 0.88 CA1 (0.68) CA1CA9ALDH1A1LMNATP53
Ethylene Glycol SCHEMBL173829 0.88 CA1 (0.76) CA1CA9ALDH1A1LMNATP53
Butyrolactone SCHEMBL5608747 0.88
Ethylene Glycol SCHEMBL31356 0.86 CA1 (0.73) CA1CA9ALDH1A1LMNATP53
Ethylene Glycol SCHEMBL1239792 0.86 CA1 (0.73) CA1CA9ALDH1A1LMNATP53
Ethylene Glycol SCHEMBL1241909 0.86 CA1 (0.73) CA1CA9ALDH1A1LMNATP53
Ethylene Glycol SCHEMBL2281708 0.86 CA1 (0.73) CA1CA9ALDH1A1LMNATP53
Ethylene Glycol SCHEMBL8524424 0.86 CA1 (0.73) CA1CA9ALDH1A1LMNATP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0811232-B1 ELECTROLYTE FOR ELECTROLYTIC CAPACITOR BOUNDARY TECH INC (US) 1999-03-10 EP disclosed
EP-0811232-A1 ELECTROLYTE FOR ELECTROLYTIC CAPACITOR BOUNDARY TECHNOLOGIES, INC. (US) 1997-12-10 EP disclosed
WO-1996019815-A9 ELECTROLYTE FOR ELECTROLYTIC CAPACITOR 1996-08-29 WO disclosed
WO-1996019815-A1 ELECTROLYTE FOR ELECTROLYTIC CAPACITOR BOUNDARY TECHNOLOGIES, INC. (US) 1996-06-27 WO disclosed
US-5496481-A DIISOPROPYLETHYLAMINE, A SOLVENT AND A CARBOXYLIC ACID AS ELECTROLYTES BOUNDARY TECHNOLOGIES, INC. (US) 1996-03-05 US disclosed