Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.64 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1727235 | 1.00 | TSHR (0.64) | TSHRCYP3A4HPGDLMNAGAA | |
| SCHEMBL17491592 | 0.90 | CYP3A4 (0.57) | TSHRCYP3A4HPGDLMNAGAA | |
| SCHEMBL27845142 | 0.88 | MEN1 (0.59) | TSHRCYP3A4HPGDLMNAMEN1 | |
| SCHEMBL7768974 | 0.84 | TSHR (0.45) | TSHRCYP3A4HPGDLMNAGAA | |
| SCHEMBL1725593 | 0.82 | TSHR (0.64) | TSHRCYP3A4HPGDLMNAGAA | |
| SCHEMBL28515962 | 0.78 | TSHR (0.59) | TSHRCYP3A4HPGDLMNAGAA | |
| SCHEMBL21582 | 0.78 | TSHR (1.00) | TSHRCYP3A4HPGDLMNAGAA | |
| SCHEMBL131412 | 0.78 | TSHR (1.00) | TSHRCYP3A4HPGDLMNAGAA | |
| SCHEMBL10336991 | 0.78 | TSHR (1.00) | TSHRCYP3A4HPGDLMNAGAA | |
| SCHEMBL27371282 | 0.78 | TSHR (1.00) | TSHRCYP3A4HPGDLMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1112313-A1 | HALOGEN-FREE FLAME RETARDANT THERMOPLASTIC POLYMER COMPOSITIONS | ALBEMARLE CORPORATION (US) | 2001-07-04 | — | — | EP | disclosed |
| WO-2000017268-A1 | HALOGEN-FREE FLAME RETARDANT THERMOPLASTIC POLYMER COMPOSITIONS | ALBEMARLE CORPORATION (US) | 2000-03-30 | — | — | WO | disclosed |