Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27845142 | 0.85 | MEN1 (0.59) | TSHRCYP3A4HPGDMEN1KMT2A | |
| SCHEMBL7768938 | 0.84 | TSHR (0.64) | TSHRCYP3A4HPGDMEN1KMT2A | |
| SCHEMBL1727235 | 0.84 | TSHR (0.64) | TSHRCYP3A4HPGDMEN1KMT2A | |
| SCHEMBL7768976 | 0.82 | L3MBTL1 (0.54) | MEN1KMT2ALMNANPSR1MAPT | |
| SCHEMBL14566897 | 0.81 | LMNA (0.55) | HPGDMEN1KMT2ALMNANPSR1 | |
| SCHEMBL3884760 | 0.79 | LMNA (0.53) | TSHRCYP3A4MEN1KMT2ALMNA | |
| SCHEMBL133405 | 0.78 | CYP3A4 (0.76) | TSHRCYP3A4HPGDMEN1KMT2A | |
| SCHEMBL17491592 | 0.78 | CYP3A4 (0.57) | TSHRCYP3A4HPGDMEN1KMT2A | |
| SCHEMBL28388783 | 0.78 | HCRTR1 (0.59) | MEN1KMT2ALMNAHTTHCRTR1 | |
| SCHEMBL7768587 | 0.77 | HPGD (0.44) | TSHRCYP3A4HPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1112313-A1 | HALOGEN-FREE FLAME RETARDANT THERMOPLASTIC POLYMER COMPOSITIONS | ALBEMARLE CORPORATION (US) | 2001-07-04 | — | — | EP | disclosed |
| WO-2000017268-A1 | HALOGEN-FREE FLAME RETARDANT THERMOPLASTIC POLYMER COMPOSITIONS | ALBEMARLE CORPORATION (US) | 2000-03-30 | — | — | WO | disclosed |