Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | NAMPT | P43490 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 3/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | SDCBP | O00560 | 1/20 | 0.46 |
| ▸ | SDC2 | P34741 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | KDM4A | O75164 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 1/20 | 0.43 |
| ▸ | XBP1 | P17861 | 1/20 | 0.43 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7768959 | 1.00 | L3MBTL1 (0.52) | L3MBTL1NAMPTGAACA1CA2 | |
| SCHEMBL3180689 | 0.88 | L3MBTL1 (0.61) | L3MBTL1NAMPTGAACA1CA2 | |
| SCHEMBL8210875 | 0.84 | NAMPT (0.54) | L3MBTL1NAMPTGAACA1CA2 | |
| SCHEMBL8372079 | 0.82 | L3MBTL1 (0.56) | L3MBTL1NAMPTGAACA1CA2 | |
| SCHEMBL1164796 | 0.82 | L3MBTL1 (0.56) | L3MBTL1NAMPTGAACA1CA2 | |
| SCHEMBL506202 | 0.82 | GAA (0.57) | L3MBTL1NAMPTGAACA1CA2 | |
| SCHEMBL12685839 | 0.82 | L3MBTL1 (0.56) | L3MBTL1NAMPTGAACA1CA2 | |
| SCHEMBL5796279 | 0.82 | L3MBTL1 (0.56) | L3MBTL1NAMPTGAACA1CA2 | |
| SCHEMBL15259134 | 0.82 | L3MBTL1 (0.56) | L3MBTL1NAMPTGAACA1CA2 | |
| SCHEMBL38655668 | 0.81 | L3MBTL1 (0.52) | L3MBTL1NAMPTGAACA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0741128-B1 | Sulphuric acid esters of sugar alcohols for the inhibition of the migration and proliferation of smooth muscle cells of the vascular walls | HOFFMANN LA ROCHE (CH) | 2001-06-20 | — | — | EP | disclosed |
| US-5830920-A | PREVENTION GROWTH OF SMOOTH MUSCLE CELLS | HOFFMANN-LA ROCHE INC. (US) | 1998-11-03 | — | — | US | disclosed |
| EP-0741128-A2 | Sulphuric acid esters of sugar alcohols for the inhibition of the migration and proliferation of smooth muscle cells of the vascular walls | F. HOFFMANN-LA ROCHE AG (CH) | 1996-11-06 | — | — | EP | disclosed |