Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LSS | P48449 | 6/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | PPARD | Q03181 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.31 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7764149 | 0.89 | LSS (0.42) | LSSALDH1A1KDM4ESMN1; SMN2HTT | |
| SCHEMBL7772349 | 0.89 | LSS (0.42) | LSSALDH1A1KDM4ESMN1; SMN2HTT | |
| SCHEMBL7768018 | 0.89 | LSS (0.42) | LSSALDH1A1KDM4ESMN1; SMN2HTT | |
| SCHEMBL7772016 | 0.87 | LSS (0.38) | LSSALDH1A1KDM4ESMN1; SMN2HTT | |
| SCHEMBL7764242 | 0.85 | CYP19A1 (0.39) | LSSALDH1A1KDM4ESMN1; SMN2HTT | |
| SCHEMBL7769431 | 0.84 | MAPK1 (0.37) | LSSALDH1A1KDM4ESMN1; SMN2HTT | |
| SCHEMBL8035630 | 0.81 | LSS (0.60) | LSSALDH1A1SMN1; SMN2HTTNPC1 | |
| SCHEMBL8035360 | 0.78 | LSS (0.47) | LSSALDH1A1SMN1; SMN2HTTNPC1 | |
| SCHEMBL7767865 | 0.77 | LSS (0.44) | LSSSMN1; SMN2HTTNPC1RAB9A | |
| SCHEMBL7681654 | 0.76 | LSS (0.68) | LSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0778264-B1 | Tertiary amines having antimycotic and cholesterol lowering activity | HOFFMANN LA ROCHE (CH) | 2001-07-11 | — | — | EP | claimed |