SCHEMBL7769064

SCHEMBL7769064

CCCCC=C=CCCCC

nearest known ligand 0.45

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 8/20 0.45
ALDH1A1 P00352 2/20 0.45
LMNA P02545 1/20 0.38
THRB P10828 1/20 0.35
DNM1 Q05193 3/20 0.33
F7 P08709 1/20 0.31
F3 P13726 1/20 0.31
FAAH O00519 2/20 0.31
TRPV1 Q8NER1 1/20 0.31
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11172833 0.94 TSHR (0.41) TSHRALDH1A1LMNATHRBDNM1
SCHEMBL7776563 0.94 TSHR (0.43) TSHRALDH1A1THRBDNM1FAAH
SCHEMBL5670052 0.91 TSHR (0.48) TSHRALDH1A1LMNATHRBDNM1
SCHEMBL28762181 0.91 TSHR (0.48) TSHRALDH1A1LMNATHRBDNM1
SCHEMBL28762164 0.91 TSHR (0.48) TSHRALDH1A1LMNATHRBDNM1
SCHEMBL29099312 0.91
SCHEMBL28762148 0.91 TSHR (0.48) TSHRALDH1A1LMNATHRBDNM1
SCHEMBL9630620 0.90 TSHR (0.46) TSHRALDH1A1THRBDNM1FAAH
SCHEMBL31509527 0.88 TSHR (0.50) TSHRLMNATHRBDNM1FAAH
SCHEMBL31508789 0.88 TSHR (0.50) TSHRLMNATHRBDNM1FAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1122295-A1 GASOLINE ADDITIVE FOR DIRECT-INJECTION GASOLINE ENGINE Nippon Mitsubishi Oil Corporation (JP) 2001-08-08 EP disclosed