Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | FAAH | O00519 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | S1PR2 | O95136 | 5/20 | 0.48 |
| ▸ | S1PR4 | O95977 | 5/20 | 0.48 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.48 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.48 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.48 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | PAOX | Q6QHF9 | 2/20 | 0.47 |
| ▸ | CASP2 | P42575 | 1/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28164599 | 0.93 | SOAT1 (0.59) | ALDH1A1TSHRSOAT1MEN1FAAH | |
| SCHEMBL28888916 | 0.93 | SOAT1 (0.59) | ALDH1A1TSHRSOAT1MEN1FAAH | |
| SCHEMBL28375298 | 0.93 | SOAT1 (0.59) | ALDH1A1TSHRSOAT1MEN1FAAH | |
| SCHEMBL28928375 | 0.93 | SOAT1 (0.59) | ALDH1A1TSHRSOAT1MEN1FAAH | |
| SCHEMBL7765758 | 0.93 | ALDH1A1 (0.56) | ALDH1A1TSHRSOAT1MEN1FAAH | |
| SCHEMBL25185288 | 0.93 | SOAT1 (0.59) | ALDH1A1TSHRSOAT1MEN1FAAH | |
| SCHEMBL28816812 | 0.93 | SOAT1 (0.59) | ALDH1A1TSHRSOAT1MEN1FAAH | |
| SCHEMBL10657120 | 0.93 | TSHR (0.50) | ALDH1A1TSHRSOAT1MEN1FAAH | |
| SCHEMBL16620178 | 0.93 | SOAT1 (0.59) | ALDH1A1TSHRSOAT1MEN1FAAH | |
| SCHEMBL13469008 | 0.93 | TSHR (0.48) | ALDH1A1TSHRSOAT1MEN1FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0765879-B1 | 13-Substituted milbemycin 5-oxime derivatives, their preparation and their use against insects and other pests | SANKYO CO (JP) | 2001-02-14 | — | — | EP | disclosed |
| US-5861429-A | MITICIDES AND ANTHELMINTICS | SANKYO COMPANY, LIMITED (JP) | 1999-01-19 | — | — | US | disclosed |
| EP-0765879-A1 | 13-Substituted milbemycin 5-oxime derivatives, their preparation and their use against insects and other pests | SANKYO COMPANY LIMITED (JP) | 1997-04-02 | — | — | EP | disclosed |