Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.38 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.38 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | DHFR | P00374 | 1/20 | 0.35 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28165836 | 0.90 | MEN1 (0.46) | MEN1KMT2ASLC6A2SLC6A4TDP1 | |
| SCHEMBL31506376 | 0.81 | MEN1 (0.40) | MEN1KMT2ASLC6A2SLC6A4TDP1 | |
| SCHEMBL11346334 | 0.78 | TAAR1 (0.50) | MEN1KMT2ASLC6A2SLC6A4TDP1 | |
| SCHEMBL11254276 | 0.78 | DPP4 (0.46) | MEN1KMT2ASLC6A2SLC6A4TDP1 | |
| SCHEMBL7050745 | 0.78 | SLC6A2 (0.63) | SLC6A2SLC6A4TDP1SLC18A2 | |
| SCHEMBL29432878 | 0.77 | TAAR1 (0.50) | MEN1KMT2AALDH1A1 | |
| SCHEMBL11455975 | 0.77 | TAAR1 (0.48) | MEN1KMT2ASLC6A2SLC6A4 | |
| SCHEMBL14290122 | 0.77 | TAAR1 (0.48) | MEN1KMT2ASLC6A2SLC6A4TDP1 | |
| SCHEMBL1499296 | 0.77 | TAAR1 (0.50) | MEN1KMT2AALDH1A1 | |
| SCHEMBL27702931 | 0.77 | MEN1 (0.40) | MEN1KMT2ASLC6A2SLC6A4TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1114029-A1 | NOVEL COMPOUNDS | AstraZeneca AB (SE) | 2001-07-11 | — | — | EP | disclosed |
| WO-2000015614-A1 | NOVEL COMPOUNDS | ASTRAZENECA AB (SE) | 2000-03-23 | — | — | WO | disclosed |