SCHEMBL1499296

SCHEMBL1499296

Fc1ccccc1CCC1CO1

nearest known ligand 0.55

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 3/20 0.50
MAOA P21397 1/20 0.44
MAOB P27338 1/20 0.44
KMT2A Q03164 2/20 0.42
PKM P14618 1/20 0.42
AOC3 Q16853 1/20 0.42
MEN1 O00255 1/20 0.40
CYP2A13 Q16696 1/20 0.40
IDO1 P14902 2/20 0.38
ALDH1A1 P00352 1/20 0.38
DRD4 P21917 1/20 0.38
MPO P05164 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.37
NPC1 O15118 1/20 0.37
PAX8 Q06710 1/20 0.37
KLF5 Q13887 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29432878 1.00 TAAR1 (0.50) TAAR1MAOAMAOBKMT2APKM
SCHEMBL7802949 0.80 KMT2A (0.44) TAAR1MAOAMAOBKMT2APKM
SCHEMBL7802952 0.80 KMT2A (0.44) TAAR1MAOAMAOBKMT2APKM
SCHEMBL11346334 0.78 TAAR1 (0.50) TAAR1MAOBKMT2AMEN1CYP2A13
SCHEMBL14290122 0.77 TAAR1 (0.48) TAAR1KMT2AMEN1IDO1ALDH1A1
SCHEMBL7769162 0.77 MEN1 (0.40) KMT2AMEN1ALDH1A1
SCHEMBL11455975 0.77 TAAR1 (0.48) TAAR1KMT2AAOC3MEN1CYP2A13
SCHEMBL31506376 0.77 MEN1 (0.40) KMT2AMEN1ALDH1A1DRD4
SCHEMBL11465666 0.77 TAAR1 (0.48) TAAR1KMT2AMEN1CYP2A13IDO1
SCHEMBL4049556 0.76 MAOA (0.62) TAAR1MAOAMAOBAOC3IDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 144 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3710159-A1 CATALYST COMPONENTS FOR PROPYLENE POLYMERIZATION W. R. Grace & Co. - Conn. (US) 2020-09-23 EP claimed
US-8344079-B2 Molar ratio modifications to larger polyolefin catalysts BASF CORPORATION (US) 2013-01-01 US claimed
JP-2011508053-A 2011-03-10 JP claimed
CN-101965369-A Molar ratio change for larger polyolefin catalysts BASF CATALYSTS LLC 2011-02-02 CN claimed
EP-2242776-A1 MOLAR RATIO MODIFICATIONS TO LARGER POLYOLEFIN CATALYSTS BASF Corporation (US) 2010-10-27 EP claimed
WO-2009088596-A1 MOLAR RATIO MODIFICATIONS TO LARGER POLYOLEFIN CATALYSTS BASF CATALYSTS LLC (US) 2009-07-16 WO claimed
US-20090171044-A1 MOLAR RATIO MODIFICATIONS TO LARGER POLYOLEFIN CATALYSTS BASF CATALYSTS LLC (US) 2009-07-02 US claimed
US-20260103548-A1 PROCESS FOR PRODUCING POLYPROPYLENE-ETHYLENE RANDOM COPOLYMER RESIN WITH SUSTAINABLE REACTOR OPERABILITY W. R. GRACE & CO.-CONN. 2026-04-16 US disclosed
EP-3592783-B1 ELECTRON DONORS FOR ZIEGLER-NATTA PRECATALYST PREPARATION AND CATALYST SYSTEM FOR OLEFIN POLYMERIZATION GRACE W R & CO (US) 2025-11-12 EP disclosed
US-20250235842-A1 GAS-PHASE PROCESS FOR MAKING POLYPROPYLENE RANDOM COPOLYMERS W.R. GRACE & CO.-CONN (US) 2025-07-24 US disclosed
US-20250145745-A1 HIGH MFR POLYPROPYLENE FOR MELTBLOWN NONWOVEN APPLICATIONS W. R. GRACE & CO.-CONN. 2025-05-08 US disclosed
US-20250109220-A1 Olefin Polymerization Catalyst Comprising Magnesium, Titanium, an Epoxy Compound and an Internal Electron Donor, Such as a 1,2-Phenylene Dibenzoate-Based Compound W. R. GRACE & CO.-CONN. 2025-04-03 US disclosed
US-12240925-B2 Process for preparing solid catalyst components for olefin polymerization W. R. GRACE & CO.- CONN. (US) 2025-03-04 US disclosed
EP-0950649-B1 A process for preparing oxyalkylene derivatives in the presence of phosphine oxides MITSUI CHEMICALS INC (JP) 2003-03-26 EP disclosed
US-6153794-A Phosphine sulfide, a manufacturing process therefor and use thereof MITSUI CHEMICALS, INC. (JP) 2000-11-28 US disclosed
US-6130346-A ESTERIFICATION, CARBONATION, SULFONATION, ETHERIFICATION MITSUI CHEMICALS, INC. (JP) 2000-10-10 US disclosed
EP-0972776-A1 A phosphine sulfide, a manufacturing process therefor and a use thereof Mitsui Chemicals, Inc. (JP) 2000-01-19 EP disclosed
CN-1235141-A Process for preparing organic compound MITSUI CHEMICALS INC (JP) 1999-11-17 CN disclosed
EP-0950649-A1 A process for preparing oxyalkylene derivatives in the presence of phosphine oxides Mitsui Chemicals, Inc. (JP) 1999-10-20 EP disclosed
US-4236012-A ANALGESICS, ANTIINFLAMMATORY AGENTS, MUSCLE RELAXANTS Nippon Chemiphar Company, Limited (JP) 1980-11-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12240925-B2 Process for preparing solid catalyst components for olefin polymerization POF1B, PPOX, OGFOD1 TAAR1 3916/4885MAOA 2958/4885MAOB 2817/4885
US-20260103548-A1 PROCESS FOR PRODUCING POLYPROPYLENE-ETHYLENE RANDOM COPOLYMER RESIN WITH SUSTAINABLE REACTOR OPERABILITY CCT4, PTGER1, TCP1 TAAR1 1463/4885MAOA 3117/4885MAOB 3617/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.