Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | LCK | P06239 | 1/20 | 0.50 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | XDH | P47989 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.47 |
| ▸ | PLAU | P00749 | 5/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.47 |
| ▸ | PLG | P00747 | 1/20 | 0.47 |
| ▸ | PLAT | P00750 | 1/20 | 0.47 |
| ▸ | KLK1 | P06870 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29365729 | 0.80 | PTPN11 (0.68) | MAPTKMT2ACA1CA2LCK | |
| SCHEMBL69025 | 0.80 | PTPN11 (0.68) | MAPTKMT2ACA1CA2LCK | |
| SCHEMBL16502423 | 0.79 | L3MBTL1 (0.44) | MAPTKMT2ALCKCYP2C9MEN1 | |
| Veratric Acid Methyl Ester SCHEMBL2050732 | 0.78 | MAPT (0.86) | MAPTKMT2ACA1CA2CYP2C9 | |
| Veratric Acid Methyl Ester SCHEMBL29573244 | 0.78 | MAPT (0.86) | MAPTKMT2ACA1CA2CYP2C9 | |
| SCHEMBL16502446 | 0.78 | CA1 (0.53) | MAPTKMT2ACA1CA2LCK | |
| SCHEMBL16509505 | 0.78 | MAPT (0.44) | MAPTKMT2AMEN1LMNA | |
| SCHEMBL16502439 | 0.78 | L3MBTL1 (0.43) | MAPTKMT2AMEN1 | |
| SCHEMBL8732524 | 0.78 | PTPN11 (0.66) | MAPTKMT2ACA1CA2LCK | |
| SCHEMBL27916584 | 0.77 | LCK (0.48) | MAPTKMT2ACA1CA2LCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0839818-B1 | Optically active diphosphines, transition metal complex containing the same, and process for producing an optically active compound using the complex | TAKASAGO PERFUMERY CO LTD (JP) | 2001-08-16 | — | — | EP | disclosed |
| US-5789609-A | CATALYST FOR ASSYMETRIC SYNTHESIS, REACTION OF AN A-CYANO ESTER AND A VINYL KETONE TO PRODUCE AN OXO CYANO ESTER | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1998-08-04 | — | — | US | disclosed |
| EP-0839818-A1 | Optically active diphosphine, transition metal complex containing the same, and process for producing optically active compound using the complex | Takasago International Corporation (JP) | 1998-05-06 | — | — | EP | disclosed |