Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 2/20 | 0.32 |
| ▸ | CES1 | P23141 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.32 |
| ▸ | IAPP | P10997 | 2/20 | 0.31 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1771453 | 0.86 | TDP1 (0.60) | TDP1MAPTKMT2ALMNACES2 | |
| SCHEMBL7765768 | 0.83 | — | — | |
| SCHEMBL7769866 | 0.82 | MAPT (0.43) | MAPTKMT2ACES2CES1ALDH1A1 | |
| SCHEMBL23735973 | 0.80 | TDP1 (0.53) | TDP1MAPTKMT2ALMNACES2 | |
| SCHEMBL12673292 | 0.80 | TDP1 (0.60) | TDP1MAPTKMT2ACES2CES1 | |
| SCHEMBL1707003 | 0.77 | TDP1 (0.56) | TDP1MAPTKMT2ACES2CES1 | |
| SCHEMBL12299385 | 0.77 | TDP1 (0.56) | TDP1MAPTKMT2ACES2CES1 | |
| SCHEMBL17776278 | 0.77 | TDP1 (0.56) | TDP1MAPTKMT2ACES2CES1 | |
| SCHEMBL13232045 | 0.77 | TDP1 (0.56) | TDP1MAPTKMT2ACES2CES1 | |
| SCHEMBL11000950 | 0.77 | TDP1 (0.56) | TDP1MAPTKMT2ACES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0765879-B1 | 13-Substituted milbemycin 5-oxime derivatives, their preparation and their use against insects and other pests | SANKYO CO (JP) | 2001-02-14 | — | — | EP | disclosed |
| US-5861429-A | MITICIDES AND ANTHELMINTICS | SANKYO COMPANY, LIMITED (JP) | 1999-01-19 | — | — | US | disclosed |
| EP-0765879-A1 | 13-Substituted milbemycin 5-oxime derivatives, their preparation and their use against insects and other pests | SANKYO COMPANY LIMITED (JP) | 1997-04-02 | — | — | EP | disclosed |