Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 6/20 | 0.44 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 4/20 | 0.42 |
| ▸ | HSP90AB1 | P08238 | 4/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HK1 | P19367 | 1/20 | 0.38 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7765684 | 0.92 | SLC29A1 (0.44) | DHFRSLC29A1CYP1A2HSP90AA1HSP90AB1 | |
| SCHEMBL7769188 | 0.92 | SLC29A1 (0.42) | DHFRSLC29A1CYP1A2HSP90AA1HSP90AB1 | |
| SCHEMBL7771297 | 0.91 | SLC29A1 (0.43) | DHFRSLC29A1CYP1A2HSP90AA1HSP90AB1 | |
| SCHEMBL7771009 | 0.90 | SLC29A1 (0.45) | DHFRSLC29A1CYP1A2HSP90AA1HSP90AB1 | |
| SCHEMBL7773535 | 0.90 | SLC29A1 (0.44) | DHFRSLC29A1CYP1A2HSP90AA1HSP90AB1 | |
| SCHEMBL7771395 | 0.89 | SLC29A1 (0.45) | DHFRSLC29A1CYP1A2HSP90AA1HSP90AB1 | |
| SCHEMBL7773551 | 0.88 | CYP1A2 (0.49) | SLC29A1CYP1A2ADORA2AADORA1CYP2C9 | |
| SCHEMBL7118739 | 0.87 | CYP3A4 (0.50) | DHFRSLC29A1CYP1A2HSP90AA1HSP90AB1 | |
| SCHEMBL7129054 | 0.85 | DHFR (0.39) | DHFRSLC29A1CYP1A2HSP90AA1HSP90AB1 | |
| SCHEMBL7131261 | 0.85 | DHFR (0.39) | DHFRSLC29A1CYP1A2HSP90AA1HSP90AB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0785208-B1 | Phosphonate nucleotide compounds | MITSUBISHI CHEM CORP (JP) | 2001-03-21 | — | — | EP | disclosed |
| EP-0785208-A1 | Phosphonate nucleotide compounds | MITSUBISHI CHEMICAL CORPORATION (JP) | 1997-07-23 | — | — | EP | disclosed |