Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.57 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 8/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7769388 | 0.93 | EPHX1 (0.61) | EPHX1MAOAMAOBACHETSHR | |
| SCHEMBL7770941 | 0.91 | EPHX1 (0.64) | EPHX1MAOAMAOBACHETDP1 | |
| SCHEMBL7771587 | 0.91 | EPHX1 (0.64) | EPHX1MAOAMAOBACHETDP1 | |
| SCHEMBL7765979 | 0.88 | EPHX1 (0.48) | EPHX1MAOAMAOBACHETSHR | |
| SCHEMBL12448046 | 0.85 | EPHX1 (0.52) | EPHX1MAOAMAOBACHETSHR | |
| SCHEMBL18890830 | 0.85 | EPHX1 (0.56) | EPHX1MAOAMAOBACHETSHR | |
| SCHEMBL7252127 | 0.83 | EPHX1 (0.77) | EPHX1ACHETSHRTDP1KDM4E | |
| SCHEMBL14433357 | 0.83 | EPHX1 (0.70) | EPHX1ACHETSHRTDP1KDM4E | |
| SCHEMBL21538522 | 0.82 | TSHR (0.61) | EPHX1ACHETSHR | |
| SCHEMBL628018 | 0.82 | EPHX1 (0.57) | EPHX1ACHETSHRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017137423-A1 | IMPROVED SULFAMIDE LINKERS FOR USE IN BIOCONJUGATES | SYNAFFIX B.V. (NL) | 2017-08-17 | — | — | WO | disclosed |
| EP-0765879-B1 | 13-Substituted milbemycin 5-oxime derivatives, their preparation and their use against insects and other pests | SANKYO CO (JP) | 2001-02-14 | — | — | EP | disclosed |
| US-5861429-A | MITICIDES AND ANTHELMINTICS | SANKYO COMPANY, LIMITED (JP) | 1999-01-19 | — | — | US | disclosed |
| EP-0765879-A1 | 13-Substituted milbemycin 5-oxime derivatives, their preparation and their use against insects and other pests | SANKYO COMPANY LIMITED (JP) | 1997-04-02 | — | — | EP | disclosed |