Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.50 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4704932 | 0.93 | ADRA1A (0.61) | EPHX1TSHRADRA1AHTTPRMT1 | |
| SCHEMBL9828955 | 0.91 | ADRA1A (0.64) | EPHX1TSHRADRA1APRMT1PLA2G4A | |
| SCHEMBL7123668 | 0.91 | ADRA1A (0.64) | EPHX1TSHRADRA1APRMT1PLA2G4A | |
| SCHEMBL6473541 | 0.91 | ADRA1A (0.64) | EPHX1TSHRADRA1APRMT1PLA2G4A | |
| SCHEMBL13213196 | 0.86 | ADRA1A (0.58) | EPHX1TSHRADRA1APRMT1PLA2G4A | |
| SCHEMBL205904 | 0.86 | EPHX1 (0.50) | EPHX1TSHRADRA1AHTTPRMT1 | |
| SCHEMBL7252127 | 0.83 | EPHX1 (0.77) | EPHX1TSHRACHE | |
| SCHEMBL14433357 | 0.83 | EPHX1 (0.70) | EPHX1TSHRACHE | |
| SCHEMBL8638899 | 0.83 | EPHX1 (0.53) | EPHX1TSHRADRA1AHTTPLA2G4A | |
| SCHEMBL21538522 | 0.82 | TSHR (0.61) | EPHX1TSHRALDH1A1EPHX2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115703736-A | Multi-target inhibitors targeting HDAC and NAD synthesis and uses thereof | 中国海洋大学 | 2023-02-17 | — | — | CN | disclosed |
| WO-2018121678-A1 | PRODRUG OF ANTIVIRAL NUCLEOSIDE ANALOGUES, AND COMPOSITION AND USE THEREOF | 广东东阳光药业有限公司 | 2018-07-05 | — | — | WO | disclosed |
| US-9175335-B2 | Biomolecule interaction using atomic force microscope | POSCO (KR) | 2015-11-03 | — | — | US | disclosed |
| EP-2852587-A1 | ANTIVIRAL COMPOUNDS WITH AN IMIDAZOLE - BIPHENYL - IMIDAZOLE CORE | Gilead Sciences, Inc. (US) | 2015-04-01 | — | — | EP | disclosed |
| EP-2850085-A1 | ANTIVIRAL COMPOUNDS INHIBITORS OF HCV NS5B | Gilead Pharmasset LLC (US) | 2015-03-25 | — | — | EP | disclosed |
| US-20140315319-A1 | BIOMOLECULE INTERACTION USING ATOMIC FORCE MICROSCOPE | POSCO (KR) | 2014-10-23 | — | — | US | disclosed |
| EP-2741746-A1 | CHEMICAL COMPOUNDS | GlaxoSmithKline LLC (US) | 2014-06-18 | — | — | EP | disclosed |
| US-8673621-B2 | Biomolecule interaction using atomic force microscope | POSTECH FOUNDATION (KR) | 2014-03-18 | — | — | US | disclosed |
| US-8647823-B2 | Polynucleotide synthesis on a modified surface | POSTECH FOUNDATION (KR) | 2014-02-11 | — | — | US | disclosed |
| WO-2014018913-A2 | SANTACRUZAMATE A COMPOSITIONS AND ANALOGS AND METHODS OF USE | UNIVERSITY OF CONNECTICUT (US) | 2014-01-30 | — | — | WO | disclosed |
| US-7547765-B2 | Branched polyalkylene glycols | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2009-06-16 | — | — | US | disclosed |
| US-20090099061-A1 | SYNTHESIS OF CAROTENOID ANALOGS OR DERIVATIVES WITH IMPROVED ANTIOXIDANT CHARACTERISTICS | CARDAX PHARMACEUTICALS, INC. | 2009-04-16 | — | — | US | disclosed |
| WO-2008118862-A1 | CAROTENOID ANALOGS AND DERIVATIVES FOR THE PREVENTION OF PLATELET AGGREGATION | CARDAX PHARMACEUTICALS, INC. (US) | 2008-10-02 | — | — | WO | disclosed |
| US-20080125350-A1 | BRANCHED POLYALKYLENE GLYCOLS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2008-05-29 | — | — | US | disclosed |
| US-20080125350-A1 | BRANCHED POLYALKYLENE GLYCOLS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2008-05-29 | — | — | US | disclosed |
| US-20080113353-A1 | Cantilevers with fixed end and free end modified by dendron | POSTECH FOUNDATION (KR) | 2008-05-15 | — | — | US | disclosed |
| US-20080064070-A1 | POLYNUCLEOTIDE SYNTHESIS ON A MODIFIED SURFACE | POSTECH FOUNDATION (KR) | 2008-03-13 | — | — | US | disclosed |
| US-7291713-B2 | Branched polyalkylene glycols | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2007-11-06 | — | — | US | disclosed |
| US-7291713-B2 | Branched polyalkylene glycols | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2007-11-06 | — | — | US | disclosed |
| US-20070128623-A1 | Cantilevers with fixed end and free end modified by dendron | POSTECH FOUNDATION (KR) | 2007-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080125350-A1 | BRANCHED POLYALKYLENE GLYCOLS | LNPEP, ANPEP, ENPEP | EPHX1 3822/4885TSHR 1429/4885ADRA1A 3910/4885 |
| US-20090099061-A1 | SYNTHESIS OF CAROTENOID ANALOGS OR DERIVATIVES WITH IMPROVED ANTIOXIDANT CHARACTERISTICS | CAT, HBZ, POLL | EPHX1 2995/4885TSHR 3277/4885ADRA1A 2277/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.